EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
8th Edition
ISBN: 9780134704227
Author: Silverthorn
Publisher: YUZU
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Chapter 18, Problem 17RQ

a.

Summary Introduction

To determine: The change in the amount of oxygen dissolved in the plasma when the PO2 of the plasma is increased.

Introduction: Blood is one of the important connective tissues in the body that helps in the transportation of gaseous molecules (oxygen and carbon dioxide mainly) and other nutrients from one part of the body to another.

b.

Summary Introduction

To explain: The change in the amount of oxygen that is bound to hemoglobin when PO2 of the plasma is increased.

Introduction: Gases travel through the blood in dissolved as well as in bounded form. This binding of gases depends on the partial pressure of the gas itself. A change in the partial pressure of the gas in blood also changes its concentration in the blood.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 18 Solutions

EBK HUMAN PHYSIOLOGY

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