Exercise Physiology: Theory and Application to Fitness and Performance
Exercise Physiology: Theory and Application to Fitness and Performance
10th Edition
ISBN: 9781259870453
Author: Scott K Powers, Edward T Howley
Publisher: McGraw-Hill Education
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Chapter 18, Problem 12SA
Summary Introduction

To describe: The thermic effect of food.

Introduction: Thermogenesis means production of heat in the body as a result of metabolic reactions due to calorie intake.

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3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L.  Measurements from preliminary tests indicate the following human pharmacokinetic parameter values:  t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%.  Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax).  (c) Estimate the maximum plasma concentration (Cmax).  (d) Estimate the time at which the plasma level first rises above 30 mg/L.  (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L.  Hint:  based on part (a) it should be apparent that the answer is less than 1hr.)  (e)…
List substitutions in your diet you could make to improve it based on what you know now about a balanced diet. For instance, if you like to drink soda, you might substitute skim milk or water for some of the soft drinks you consumed. List the item you wish to replace with the new item and what you hope to accomplish with that substitution. Be sure to choose foods you know that you'd enjoy and you consider more "healthful." If you feel your diet is already balanced, describe how you accomplish your balanced intake and when you began eating this way.
Which single food item contained you ate for the 3 days with the most sodium?
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