Myxedema, endemic goiter, and toxic goiter. Introduction: The thyroid gland consists of two lobes; it is the largest adult endocrine gland (weighing about 25 grams). The isthmus connects the two lobes of the thyroid gland. The thyroid is located at the neck, adjacent to the trachea, and beneath the larynx. It appears in a butterfly shape and is covered around the trachea. It is composed of thyroid follicles that are covered by follicular cells. The follicular cells secret thyroid hormones (TH) such as triiodothyronine (T 3 ) and thyroxine (T 4 ). The thyroid gland releases TH into the bloodstream. Thyroid hormones act by binding to their thyroid hormone receptors (TR), which is a superfamily of nuclear receptors. TR encoding genes are classified into α (TRα) and β (TRβ). Thyroid stimulating hormone (TSH) regulates hormones’ (T 3 and T 4 ) secretion from the thyroid. TH raises the metabolic rate by promoting the adequate supply of blood and oxygen. Also, TH increases the heart rate and respiratory rate, and is involved in the breakdown of carbohydrates and fats to provide energy. TH regulates appetite, alertness, the secretion of the growth hormone, body growth, reproduction, and the circulatory system. Abnormal secretion of thyroid hormones may cause thyroid problems.

Question

Want to see the full answer?

Answer 1

Question

Chapter 17.7, Problem 2AYLO

Summary Introduction

To discuss:

Myxedema, endemic goiter, and toxic goiter.

Introduction:

The thyroid gland consists of two lobes; it is the largest adult endocrine gland (weighing about 25 grams). The isthmus connects the two lobes of the thyroid gland. The thyroid is located at the neck, adjacent to the trachea, and beneath the larynx. It appears in a butterfly shape and is covered around the trachea. It is composed of thyroid follicles that are covered by follicular cells. The follicular cells secret thyroid hormones (TH) such as triiodothyronine (T₃) and thyroxine (T₄). The thyroid gland releases TH into the bloodstream. Thyroid hormones act by binding to their thyroid hormone receptors (TR), which is a superfamily of nuclear receptors. TR encoding genes are classified into α (TRα) and β (TRβ). Thyroid stimulating hormone (TSH) regulates hormones’ (T₃ and T₄) secretion from the thyroid. TH raises the metabolic rate by promoting the adequate supply of blood and oxygen. Also, TH increases the heart rate and respiratory rate, and is involved in the breakdown of carbohydrates and fats to provide energy. TH regulates appetite, alertness, the secretion of the growth hormone, body growth, reproduction, and the circulatory system. Abnormal secretion of thyroid hormones may cause thyroid problems.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

What is behavioral adapt

22. Which of the following mutant proteins is expected to have a dominant negative effect when over- expressed in normal cells? a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function b. mutant Grb2 protein that cannot bind to RTK c. mutant RTK that lacks the extracellular domain d. mutant PDK that has the PH domain but lost the kinase function e. all of the above

What is the label ?