Genetics: A Conceptual Approach 6E w/ SaplingPlus (Six-Month Access)
Genetics: A Conceptual Approach 6E w/ SaplingPlus (Six-Month Access)
6th Edition
ISBN: 9781319125929
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Chapter 17.2, Problem 19AQP
Summary Introduction

To explain:

The reason that why X31b might be an effective drug.

Introduction:

Gene regulation is a mechanism which acts to either induce or repress the gene expression. The DNA methylation of base cytosine resulting in 5-methylcytosine results in repression of transcription. Methylation helps in removing acetyl group present in the histone tails and stabilizes and represses transcription. Effective cancer drugs are designed by their action of inhibiting the rapid transcription cancerous cells.

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calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data.show solving and answer a) B1,   b) B2,   c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist t1/2,absorb f) t1/2,elim   k) apparent central compartment volume (V1,app) p) total AUC (using short cut method) apparent volume of distribution based on AUC (VAUC,app)  apparent clearance (CLapp)   absolute bioavailabilty of oral route ( AUCiv =116ml)
Please help me to draw this by hand. In as much detail as possible, hand draw a schematic diagram of the hypothalamic-pituitary-gonad (HPG) axis in the human female. Be sure to include all the relevant structures and hormones. You must define all abbreviations the first time you use them. Please include (and explain) the feedback loops.
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