MindTap for Des Jardins' Cardiopulmonary Anatomy & Physiology, 2 terms Printed Access Card
MindTap for Des Jardins' Cardiopulmonary Anatomy & Physiology, 2 terms Printed Access Card
7th Edition
ISBN: 9781337794923
Author: Des Jardins, Terry
Publisher: Cengage Learning
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Chapter 17, Problem 5RQ
Summary Introduction

Introduction:

Sleep disorders are defined as changes in the regular sleep pattern of an individual. Sleep is a necessary factor in maintaining a healthy work-life balance. Sleep disorders occur due to various reasons, such as a change in lifestyle, drug intake, pathological disorders, heredity, and many other factors.

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Draw a rough sketch of the control and experimental data using a normal dose/response curve plot: i.e. % of total bound ligand vs. concentration. Indicate Kd and Bmax on this sketch. You don’t need to use exact numbers, but the relative proportions should be close
Name something that could be happening to glutamate transporters that could have this effect on glutamate transport (i.e. the difference in glutamate transporters between control and experimental conditions). (Bonus: if you can also guess what the experimental condition is).
a. For the control condition, calculate Kd. Include units and show your work. b. For the control condition, calculate Bmax. Include units and show your work.  c. For the experimental condition, calculate Kd. Include units and show your work. For the experimental condition, calculate Bmax. Include units and show your work.
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