For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained Concept introduction: Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine The requirement of an odd number of electron pair is called Huckel’s rule . A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic. Each π bond count as two π electron and lone pair also count as two π electron

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Answer 1

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Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 17, Problem 56IP

Interpretation Introduction

Interpretation: For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained

Concept introduction:

Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property

Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine

The requirement of an odd number of electron pair is called Huckel’s rule. A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic.

Each π bond count as two π electron and lone pair also count as two π electron

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2. 200 LOD For an unknown compound with a molecular ion of 101 m/z: a. Use the molecular ion to propose at least two molecular formulas. (show your work) b. What is the DU for each of your possible formulas? (show your work) C. Solve the structure and assign each of the following spectra. 8 6 4 2 (ppm) 150 100 50 ō (ppm) 4000 3000 2000 1500 1000 500 HAVENUMBERI-11

Answer 2

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Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 17, Problem 56IP

Interpretation Introduction

Interpretation: For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained

Concept introduction:

Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property

Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine

The requirement of an odd number of electron pair is called Huckel’s rule. A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic.

Each π bond count as two π electron and lone pair also count as two π electron

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Answer 3

Question

Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 17, Problem 56IP

Interpretation Introduction

Interpretation: For the given compounds, which hold greater promise as a potential anti histamine should be found and its sedative property should explained

Concept introduction:

Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting. Which have sedative property

Anti-histamines required pharmacophore, is a part of molecular structure that has two aromatic rings separated by one carbon atom, and a tertiary amine

The requirement of an odd number of electron pair is called Huckel’s rule. A compound can only be aromatic if the number of π electron in the ring is 2, 6,10,14,18 and so on. This series of number can be expressed mathematically as 4n+2 , where n should be an integer and the compound is aromatic.

Each π bond count as two π electron and lone pair also count as two π electron

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Rule that estimates whether a given organic planar ring structure will show an aromatic property. A cyclic ring molecule is said to follow Hückel’s rule if the л-electrons count in a molecule is [4n+2], where n stands for a positive numerical value. It is also called the [4n+2] rule. Hückel's rule, sometimes referred to as the aromaticity rule, is one but not the only criteria to judge a molecule for aromaticity.

Chapter 17, Problem 56IP

Interpretation Introduction