ORGANIC CHEMISTRY (LOOSELEAF)-PACKAGE
ORGANIC CHEMISTRY (LOOSELEAF)-PACKAGE
10th Edition
ISBN: 9781260008562
Author: Carey
Publisher: MCG
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Chapter 17, Problem 35P
Interpretation Introduction

Interpretation:

The stereochemical configuration of the propranolol formed by the given sequence is to be stated.

Concept introduction:

Epoxides undergo nucleophilic ring opening reactions which are acid-catalyzed.

If the epoxide is unsymmetrical, then the anionic nucleophile will attack the less-hindered carbon atom of the ring.

If the reaction conditions are acidic, then the reaction will occur at the more substituted carbon atom.

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Chapter 17 Solutions

ORGANIC CHEMISTRY (LOOSELEAF)-PACKAGE

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