Human Biology: Concepts and Current Issues
7th Edition
ISBN: 9780321821652
Author: Michael D. Johnson
Publisher: Benjamin Cummings
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Chapter 17, Problem 2TY
Summary Introduction
Introduction:
Each cell undergoes the cell cycle. It is the cycle that leads to the creation of new cells from existing cells. It consists of interphase and mitosis. Interphase takes up most of the duration of the cell cycle. It is the phase in which the cell undergoes growth and prepares for cell division. There are sub-phases in interphase: Gap 1 or G1, Synthesis or S phase, and Gap 2 or G2.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 17 Solutions
Human Biology: Concepts and Current Issues
Ch. 17 - Do you think the potential benefits of therapeutic...Ch. 17 - Should research leading to human reproductive...Ch. 17 - Describe how DNA is replicated before cell...Ch. 17 -
2. Compare and contrast the processes of...Ch. 17 - Explain what mutations are and the role of DNA...Ch. 17 - Name the four phases of mitosis and describe...Ch. 17 -
5. Explain why only one large egg is formed...Ch. 17 - Describe what is meant by selective gene...Ch. 17 - Explain how factors present in the environment can...Ch. 17 - Describe how ribosomes contribute to the formation...
Ch. 17 - Prob. 9CRCh. 17 - Prob. 10CRCh. 17 - What would be the outcome if a cell completed...Ch. 17 - Prob. 2TYCh. 17 - Prob. 3TYCh. 17 - Prob. 4TYCh. 17 - Which of the following are listed in order from...Ch. 17 - Prob. 6TYCh. 17 - Which is likely to be the shortest chain of...Ch. 17 - How many different amino acids could be encoded if...Ch. 17 - Prob. 9TYCh. 17 - Why do cells within an organism differentiate,...Ch. 17 - Which method of cloning is most similar to the way...Ch. 17 - Prob. 12TYCh. 17 - Prob. 13TYCh. 17 - Prob. 14TYCh. 17 -
15. How does the production of sperm differ from...Ch. 17 - Prob. 1AWKCh. 17 - Prob. 2AWKCh. 17 - Prob. 3AWKCh. 17 - Prob. 4AWKCh. 17 - Mitochondria contain their own DNA that is...Ch. 17 - Bacteria can reproduce by simple cell division....
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