Human Biology: Concepts and Current Issues
Human Biology: Concepts and Current Issues
7th Edition
ISBN: 9780321821652
Author: Michael D. Johnson
Publisher: Benjamin Cummings
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Chapter 17, Problem 2TY
Summary Introduction

Introduction:

Each cell undergoes the cell cycle. It is the cycle that leads to the creation of new cells from existing cells. It consists of interphase and mitosis. Interphase takes up most of the duration of the cell cycle. It is the phase in which the cell undergoes growth and prepares for cell division. There are sub-phases in interphase: Gap 1 or G1, Synthesis or S phase, and Gap 2 or G2.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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