![EBK THE IMMUNE SYSTEM, 4E](https://www.bartleby.com/isbn_cover_images/8220100542800/8220100542800_largeCoverImage.jpg)
(a)
To Determine:
If the given statement is true or false.
Introduction:
Cancer is a disease caused due to the metastasis of tumor cells to different parts of the body. It can occur due to a mutation in tumor suppressor gene and proto-oncogenes, viruses, radiation and carcinogens.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The given statement is true.
Explanation of Solution
Old people are more susceptible to disease such as cancer due to reduced immunity and accumulation of mutations over time. A few mutations might not cause any issue, however the accumulation of these mutations as one grows old leads to cancer.
(b)
To Determine:
If the given statement is true or false should be determined.
Introduction:
Industrialized societies with better health facilities due to advancement in the field of science and technology have higher life expectancies. It also means that there is more time for the damages caused in the cells due to mutations to accumulate and eventually disturb the cell cycle.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The statement is true.
Explanation of Solution
The rate of cancer are higher in industrialized societies that have longer life expectancies. Longer age leads to accumulation of more mutations that have a higher chance of disturbing the cell cycle. An unregulated cell cycle due to these changes in the cells leads to higher cases of cancer in such societies.
(c)
To Determine:
If the given statement is true or false should be determined.
Introduction:
Cancer can arise due to a variety of factors. These factors include exposure to radiation, carcinogens, accumulation of random mutations, infection by cancer-causing viruses, hormonal imbalance, and obesity.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The statement is false.
Explanation of Solution
A single mutation usually does not abolishes the entire control of the cell cycle as it is regulated at various levels. Cancer is caused due to the accumulation of such mutations that disturb the cell cycle regulation at multiple levels.
(d)
To Determine:
If the given statement is true or false should be determined.
Introduction:
The immune system plays an important role in protecting the body from any foreign antigen. The cancer cells project some different set of proteins on their membrane, which can be identified by the immune system leading to their elimination.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The statement is true.
Explanation of Solution
The cancer cells are eliminated by the dendritic cells of the immune system much like the virus elimination. The dendritic cells has the ability to present the proteins of the cancer to the T-cells, which then produce cytokines to activate various immune response for the elimination of affected cells.
(e)
To Determine:
If the given statement is true or false should be determined.
Introduction:
Remission is a case wherein the cancer case completely gone and a partial remission means that the patient can pause the treatment for some time, however, there are chances for cancer to bounce back.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The statement is false.
Explanation of Solution
Most of the cancers have a chance of bouncing back as soon as the treatment is stopped. This can occur due to the survival of some cancer cells during the treatment. The cells are very small and are spread across the body due to metastasis that they might miss the eye of a doctor.
(f)
To Determine:
If the given statement is true or false should be determined.
Introduction:
Proto-oncogenes encode for a protein that regulated the cell cycle. Mutation in these genes leads to the formation of oncogenes that can cause the disturbance in the cycle, eventually leading to cancer.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The statement is false.
Explanation of Solution
Cancer can be caused due to a variety of factors including inheritance, smoking, tobacco, obesity, hormonal imbalance, and viruses. Although viruses are one of the causes of cancer, they are not the number one cause of cancer.
(g)
To Determine:
If the given statement is true or false should be determined.
Introduction:
Immunosuppressant reduces the capacity of the body to fight infections by suppressing the immune cells. This paves the way for infections and mutations without getting noticed by the body which increases the risk of cancer.
![Check Mark](/static/check-mark.png)
Answer to Problem 1Q
The statement is true.
Explanation of Solution
Immunosuppressant reduces the ability of the body to fight infections and notice any mutated cells. Usually, the mutated cells are eliminated by the immune cells as the mutated proteins are recognized by these cells presented by major histocompatibility complexes on their membranes. If their activity of reduced these cells keeps accumulating mutations increasing the risk of cancer.
Want to see more full solutions like this?
Chapter 17 Solutions
EBK THE IMMUNE SYSTEM, 4E
- , if one of the archaeological specimens lacked the celiac disease-causing epitope, how could PCR be used to identify the allele in a contemporary germplasm collection of wild wheats, and to assist in transferring the allele to modern wheat varieties?arrow_forwardNow you will consider the composition of lipoproteins, including where they are synthesized, how they circulate, and where the various lipid and protein components are located within the lipoprotein molecule. Drag the appropriate labels to their respective targets.arrow_forwardThe Oregon Wolfe Barley mapping population is unique in having 12 easily-scored morphological markers, each showing monogenic inheritance. Do you consider these markers useful? Briefly defend your answer, pointing out advantages and disadvantages of morphological vs. molecular markers.arrow_forward
- Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions Calculate these : a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forwardIn a population of Jackalopes (pictured below), horn length will vary between 0.5 and 2 feet, with the mean length somewhere around 1.05 feet. You pick Jackalopes that have horn lengths around 1.75 feet to breed as this appears to be the optimal length for battling other Jackalopes for food. After a round of breeding, you measure the offsprings' mean horn length is 1.67. What is the heritability of horns length (h2)? Is Jackalope horn length a heritable trait? (4 pts)? 12pt v R Paragraph V BIU A श्र > Barrow_forwardThere are many differences between DNA replication happening during mitosis in a Douglas fir tree growing in the Oregon Cascade Mountains and DNA replication happening during a PCR reaction in a forestry research lab at Oregon State University where the laboratory is amplifying a Simple Sequence Repeat. Complete the following table that compares the two DNA replication events in terms of the primers, the nucleotides, the polymerase, and the target sequence. Additionally, give a general value for the number of copies of the template DNA after one S phase in one cell and after the lab has completed the PCR reaction. Tree SSR Type your answer here: Primers Nucleotides Polymerase Target sequence Number of copiesarrow_forward
- Describe how insulin binding to its receptor induces glucose uptake in healthy individuals. Please specifyeach step in the cascade and use a diagram to illustrate the answer.arrow_forwardThere is a patient with breast cancer, after staining the breast tissue with H&E, state the molecular subtype of the tumour extracted. Results of H&E staining are down belowarrow_forwardBiopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions Calculate these : a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forward
- Use the Henderson-Hasselbalch equation for a propanoic acid solution (CH₂CH₂CO₂H, pK₁ = 4.874) to calculate the quotient [A-]/[HA] at three different pH values. pH = 4.479 [A-] [HA] [A-] pH = 4.874 [HA] = pH = 5.220 [A-] = [HA]arrow_forwardIn order to establish the expiration date of perishable food, growth curve data must be collected. Once the microbial load is so high that it poses a hazard to human health, the food item is no longer considered safe (expired). Generally a load of x50,000 bacteria/gram is considered unsafe. Your task is to determine the microbial growth curves for MicroYo, a new brand of yogurt. The growth is determined by sampling the yogurt and growing the bacterial isolates in broth culture which is then serially diluted by a total of x10,000 and inoculated onto standard petri plates of nutrient agar. The following colony counts are measured: Time (days) MicroYo colony count# 1 1 4 1 12 2 16 20 4 7 What day should you recommend expiring the yogurt (the last possible date before the microbial load is unsafe). 12 4 20 16arrow_forward9. Chicken combs in chickens is an example where you see interactions between genes. See potential genotypes and phenotypes below. Which genotype, when mated to a rose comb chicken, will produce progeny that are 50% walnut comb and 50% pea comb? walnut (RRPP) walnut (RrPP) pea (rrPP) walnut (RRPP) walnut (RrPp) pea (rrPp) rose rose single (RRPP) (Rrpp) (rrpp)arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
![Text book image](https://www.bartleby.com/isbn_cover_images/9780134580999/9780134580999_smallCoverImage.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9781259398629/9781259398629_smallCoverImage.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9780815344322/9780815344322_smallCoverImage.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260159363/9781260159363_smallCoverImage.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260231700/9781260231700_smallCoverImage.gif)