Which round of the citric acid cycle will release labeled CO 2 , if the carbonyl carbon of acetyl CoA is labeled with 14 C. Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO 2 . If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

Here is my literature Beta Carotene HPLC analysis graph. Can you help me explain what each peak is at each retention time? Thank You :D

I have a literature B-Carotene HPLC graph in which showcases a retention time of roughly 23.6 and 25.1. Please help me compare my two different Anti-Oxidant Juice graphs. (Attached) The juices provided are: V8 Carrot Ginger Blend and V8 Original Blend Noticing the HPLC graphs I saw no peaks for the Original Blend for B-Carotene. However the Carrot Ginger Blend showed similar peaks --> Why is this reason? Please explain in terms of Retention time and Area (Under Curve). Thank You!

Calculate pH of a solution prepared by dissolving 1.60g of sodium acetate, in 88.5 mL of 0.10 M acetic acid. Assume the volume change upon dissolving the sodium acetate is negligible. Ka is 1.75 x 10^-5

Answer 2

Question

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.

Answer 6

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.

Answer 7

Chapter 17, Problem 1E

Summary Introduction

To explain: Which round of the citric acid cycle will release labeled CO₂, if the carbonyl carbon of acetyl CoA is labeled with ¹⁴C.

Concept introduction: The pyruvate produced from the glycolysis can enter the citric acid cycle as acetyl CoA and splits into CO₂. If the carbonyl carbon of acetyl CoA is labeled, it becomes C4 of the succinyl-CoA.

Answer 8

Expert Solution & Answer

Explanation of Solution

Explanation:

Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle and forms citrate on reaction with oxaloacetate. The labeled carbonyl carbon of the acetyl CoA becomes C4 of the succinyl-CoA. The CO₂ produced in the first round is from the oxaloacetate carbon. The carbon of acetyl CoA is not produced as CO₂ in the first round. When the labeled succinyl-CoA enters the second round, the labeled carbon is produced as CO₂ by the action of isocitrate dehydrogenase and the ketoglutarate dehydrogenase enzymes.