It is to be shown how the given synthesis would carry out using necessary reagents. Concept introduction: Sodium hydride (NaH) is an ionic hydride and thus a strong base; it can be used to abstract the proton, resulting in the formation of nucleophile. Lithium dialkylcuprates ( R 2 CuLi ) are weak R - nucleophiles that favor conjugate addition over direct addition. The Wittig reaction is one of the primer methods of preparation of alkene from aldehyde or ketone using a reagent called ylide. The ylide is a neutral molecule having positively charged phosphorous atom bonded to negatively charged carbon atom. The negatively charged carbon of an ylide acts as a nucleophile and attacks the electrophilic carbon of carbonyl group and forms betaine, which has the negative charge on oxygen and positive charge on phosphorus atom.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 17, Problem 17.78P

Interpretation Introduction

Interpretation:

It is to be shown how the given synthesis would carry out using necessary reagents.

Concept introduction:

Sodium hydride (NaH) is an ionic hydride and thus a strong base; it can be used to abstract the proton, resulting in the formation of nucleophile.

Lithium dialkylcuprates (R2CuLi) are weak R- nucleophiles that favor conjugate addition over direct addition.

The Wittig reaction is one of the primer methods of preparation of alkene from aldehyde or ketone using a reagent called ylide. The ylide is a neutral molecule having positively charged phosphorous atom bonded to negatively charged carbon atom. The negatively charged carbon of an ylide acts as a nucleophile and attacks the electrophilic carbon of carbonyl group and forms betaine, which has the negative charge on oxygen and positive charge on phosphorus atom.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Can you please explain to me this problem im very confused and lost. Help me step by step and in detail im soo lost.

2) There are many forms of cancer, all of which involve abnormal cell growth. The growth and production of cells, called cell proliferation, is known to involve an enzyme called protein farnesyltransferase (PFTase). It is thought that inhibitors pf PFTase may be useful as anticancer drugs. The following molecule showed moderate activity as a potential PFTase inhibitor. Draw all stereoisomers of this compound. HO OH

Considering rotation around the bond highlighted in red, draw the Newman projection for the most stable and least stable conformations when viewed down the red bond in the direction of the arrow. Part 1 of 2 H₁₂C H H Draw the Newman projection for the most stable conformation. Select a template to begin. Part 2 of 2 Draw the Newman projection for the least stable conformation. G 心

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 17, Problem 17.78P

Interpretation Introduction

Interpretation:

It is to be shown how the given synthesis would carry out using necessary reagents.

Concept introduction:

Sodium hydride (NaH) is an ionic hydride and thus a strong base; it can be used to abstract the proton, resulting in the formation of nucleophile.

Lithium dialkylcuprates (R2CuLi) are weak R- nucleophiles that favor conjugate addition over direct addition.

The Wittig reaction is one of the primer methods of preparation of alkene from aldehyde or ketone using a reagent called ylide. The ylide is a neutral molecule having positively charged phosphorous atom bonded to negatively charged carbon atom. The negatively charged carbon of an ylide acts as a nucleophile and attacks the electrophilic carbon of carbonyl group and forms betaine, which has the negative charge on oxygen and positive charge on phosphorus atom.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 17, Problem 17.78P

Interpretation Introduction

Interpretation:

It is to be shown how the given synthesis would carry out using necessary reagents.

Concept introduction:

Sodium hydride (NaH) is an ionic hydride and thus a strong base; it can be used to abstract the proton, resulting in the formation of nucleophile.

Lithium dialkylcuprates (R2CuLi) are weak R- nucleophiles that favor conjugate addition over direct addition.

The Wittig reaction is one of the primer methods of preparation of alkene from aldehyde or ketone using a reagent called ylide. The ylide is a neutral molecule having positively charged phosphorous atom bonded to negatively charged carbon atom. The negatively charged carbon of an ylide acts as a nucleophile and attacks the electrophilic carbon of carbonyl group and forms betaine, which has the negative charge on oxygen and positive charge on phosphorus atom.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 17, Problem 17.78P

Interpretation Introduction