Chapter 17, Problem 17.78P

Interpretation Introduction

Interpretation:

It is to be shown how the given synthesis would carry out using necessary reagents.

Concept introduction:

Sodium hydride (NaH) is an ionic hydride and thus a strong base; it can be used to abstract the proton, resulting in the formation of nucleophile.

Lithium dialkylcuprates $\left({\text{R}}_{\text{2}}\text{CuLi}\right)$ are weak ${\text{R}}^{\text{-}}$ nucleophiles that favor conjugate addition over direct addition.

The Wittig reaction is one of the primer methods of preparation of alkene from aldehyde or ketone using a reagent called ylide. The ylide is a neutral molecule having positively charged phosphorous atom bonded to negatively charged carbon atom. The negatively charged carbon of an ylide acts as a nucleophile and attacks the electrophilic carbon of carbonyl group and forms betaine, which has the negative charge on oxygen and positive charge on phosphorus atom.