Anatomy and Physiology
9th Edition
ISBN: 9781260256000
Author: SALADIN
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 16.4, Problem 7AYLO
The bony and membranous labyrinths of the inner ear; the names and distribution of the two inner-ear fluids in relation to the labyrinths
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Outline a method for using apomixis to maintain feminized CannabisAssume apomixis is controlled by a single dominant gene. You can choose the type of apomixis: obligate or facultative, gametophytic or sporophytic. Discuss advantages and disadvantages of your proposed method.
Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug:
(a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate)
(b) Estimate the time for maximum plasma concentration (tmax).
(c) Estimate the maximum plasma concentration (Cmax).
(d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.)
(e)…
Chapter 16 Solutions
Anatomy and Physiology
Ch. 16.1 - Not every sensory receptor is a sense organ....Ch. 16.1 - What does it mean to say sense organs are...Ch. 16.1 - Prob. 3BYGOCh. 16.1 - What is meant by the modality of a stimulus? Give...Ch. 16.1 - Three schemes of receptor classification were...Ch. 16.1 - Nociceptors are tonic rather than phasic...Ch. 16.1 - The definition of receptor and the range of...Ch. 16.1 - Prob. 2AYLOCh. 16.1 - Prob. 3AYLOCh. 16.1 - Prob. 4AYLO
Ch. 16.1 - Prob. 5AYLOCh. 16.1 - Prob. 6AYLOCh. 16.1 - Prob. 7AYLOCh. 16.2 - What stimulus modalities are detected by free...Ch. 16.2 - Prob. 8BYGOCh. 16.2 - Where do most second-order somatosensory neurons...Ch. 16.2 - Explain the phenomenon of referred pain in terms...Ch. 16.2 - Explain the roles of bradykinin, substance P, and...Ch. 16.2 - Prob. 12BYGOCh. 16.2 - Three Types of unencapsulated sensory nerve...Ch. 16.2 - Six types of encapsulated nerve endings and how...Ch. 16.2 - The main routes for somatosensory signals from the...Ch. 16.2 - Definitions of pain and nociceptorCh. 16.2 - Differences between fast pain and slow painCh. 16.2 - Differences between somatic and visceral pain, and...Ch. 16.2 - Several chemicals released by injured tissues that...Ch. 16.2 - The general three-neuron pathway typically taken...Ch. 16.2 - Pain pathways from receptors in the head to the...Ch. 16.2 - Pain pathways from the lower body to the cerebral...Ch. 16.2 - Prob. 11AYLOCh. 16.2 - Referred pain and its anatomical basisCh. 16.2 - Prob. 13AYLOCh. 16.2 - Prob. 14AYLOCh. 16.3 - Prob. 13BYGOCh. 16.3 - Prob. 14BYGOCh. 16.3 - Prob. 15BYGOCh. 16.3 - Prob. 16BYGOCh. 16.3 - Prob. 17BYGOCh. 16.3 - Prob. 1AYLOCh. 16.3 - Types, locations, and functions of lingual...Ch. 16.3 - Five primary taste sensations, and sensations...Ch. 16.3 - Prob. 4AYLOCh. 16.3 - Prob. 5AYLOCh. 16.3 - Prob. 6AYLOCh. 16.3 - How odor molecules excite olfactory cellsCh. 16.3 - Prob. 8AYLOCh. 16.3 - Prob. 9AYLOCh. 16.3 - Prob. 10AYLOCh. 16.4 - Prob. 18BYGOCh. 16.4 - Prob. 19BYGOCh. 16.4 - Prob. 20BYGOCh. 16.4 - Prob. 21BYGOCh. 16.4 - Prob. 22BYGOCh. 16.4 - Why can't we see wavelengths of 350 nm or 750 nm?Ch. 16.4 - Prob. 1AYLOCh. 16.4 - Prob. 2AYLOCh. 16.4 - Prob. 3AYLOCh. 16.4 - Prob. 4AYLOCh. 16.4 - Prob. 5AYLOCh. 16.4 - Prob. 6AYLOCh. 16.4 - The bony and membranous labyrinths of the inner...Ch. 16.4 - Prob. 8AYLOCh. 16.4 - Prob. 9AYLOCh. 16.4 - Prob. 10AYLOCh. 16.4 - Prob. 11AYLOCh. 16.4 - Prob. 12AYLOCh. 16.4 - Prob. 13AYLOCh. 16.4 - Prob. 14AYLOCh. 16.4 - The pathway from cochlear nerve to auditory...Ch. 16.4 - Prob. 16AYLOCh. 16.4 - Prob. 17AYLOCh. 16.4 - Prob. 18AYLOCh. 16.4 - Prob. 19AYLOCh. 16.4 - Prob. 20AYLOCh. 16.4 - Prob. 21AYLOCh. 16.4 - The path taken by signals in the vestibular nerve...Ch. 16.4 - Prob. 23AYLOCh. 16.5 - Prob. 24BYGOCh. 16.5 - Prob. 25BYGOCh. 16.5 - Prob. 26BYGOCh. 16.5 - Prob. 27BYGOCh. 16.5 - Prob. 28BYGOCh. 16.5 - Prob. 1AYLOCh. 16.5 - Six extrinsic eye muscles, their anatomy, the eye...Ch. 16.5 - Prob. 3AYLOCh. 16.5 - Prob. 4AYLOCh. 16.5 - Prob. 5AYLOCh. 16.5 - Prob. 6AYLOCh. 16.5 - Prob. 7AYLOCh. 16.5 - General structure of the retina: its two points of...Ch. 16.5 - Prob. 9AYLOCh. 16.5 - Prob. 10AYLOCh. 16.5 - Principles of refraction; points at which...Ch. 16.5 - The difference between enmetropia and lite near...Ch. 16.5 - Histological layers and cell types of the retina....Ch. 16.5 - The structures of rods and cones; where visual...Ch. 16.5 - Differences in rod and cone functionCh. 16.5 - Prob. 16AYLOCh. 16.5 - Prob. 17AYLOCh. 16.5 - Why a single retinal receptor system cannot...Ch. 16.5 - Difference between S, M, and L cones; how neural...Ch. 16.5 - Prob. 20AYLOCh. 16.5 - Prob. 21AYLOCh. 16.5 - Hemidecussation, where it occurs, and how it...Ch. 16.5 - Prob. 23AYLOCh. 16 - Hot and cold stimuli are detected by a. free nerve...Ch. 16 - _____is a neurotransmitter that transmits pain...Ch. 16 - Prob. 3TYRCh. 16 - Prob. 4TYRCh. 16 - Prob. 5TYRCh. 16 - Prob. 6TYRCh. 16 - Prob. 7TYRCh. 16 - Prob. 8TYRCh. 16 - The retina receives its oxygen supply from a. the...Ch. 16 - Prob. 10TYRCh. 16 - The most finely detailed vision occurs when an...Ch. 16 - Prob. 12TYRCh. 16 - Prob. 13TYRCh. 16 - Prob. 14TYRCh. 16 - Three rows of________in the cochlea have V-shaped...Ch. 16 - The ______ is a tiny bone that vibrates in the...Ch. 16 - The _____ of the midbrain receives auditory input...Ch. 16 - Prob. 18TYRCh. 16 - Olfactory neurons synapse with mitral cells and...Ch. 16 - In the phenomenon of ______, pain from the viscera...Ch. 16 - bin-Ch. 16 - decuss-Ch. 16 - hemi-Ch. 16 - lacrimo-Ch. 16 - litho-Ch. 16 - maculo-Ch. 16 - noci-Ch. 16 - scoto-Ch. 16 - -sepsisCh. 16 - Prob. 10BYMVCh. 16 - The sensory (afferent) nerve fibers for touch end...Ch. 16 - Prob. 2WWTSCh. 16 - Things we see with the left eye are perceived only...Ch. 16 - Prob. 4WWTSCh. 16 - The vitreous body occupies the posterior chamber...Ch. 16 - Prob. 6WWTSCh. 16 - Prob. 7WWTSCh. 16 - Prob. 8WWTSCh. 16 - Prob. 9WWTSCh. 16 - Prob. 10WWTSCh. 16 - The principle of neural convergence is explained...Ch. 16 - What type of cutaneous receptor enables you to...Ch. 16 - Prob. 3TYCCh. 16 - Prob. 4TYCCh. 16 - Prob. 5TYC
Additional Science Textbook Solutions
Find more solutions based on key concepts
True or false? Some trails are considered vestigial because they existed long ago.
Biological Science (6th Edition)
1. Rub your hands together vigorously. What happens? Discuss the energy transfers and transformations that take...
College Physics: A Strategic Approach (3rd Edition)
56. Global Positioning System. Learn more about the global positioning system and its uses. Write a short repo...
The Cosmic Perspective (8th Edition)
Single penny tossed 20 times and counting heads and tails: Probability (prediction): _______/20 heads ________/...
Laboratory Manual For Human Anatomy & Physiology
How does the removal of hydrogen atoms from nutrient molecules result in a loss of energy from the nutrient mol...
SEELEY'S ANATOMY+PHYSIOLOGY
An obese 55-year-old woman consults her physician about minor chest pains during exercise. Explain the physicia...
Biology: Life on Earth with Physiology (11th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- List substitutions in your diet you could make to improve it based on what you know now about a balanced diet. For instance, if you like to drink soda, you might substitute skim milk or water for some of the soft drinks you consumed. List the item you wish to replace with the new item and what you hope to accomplish with that substitution. Be sure to choose foods you know that you'd enjoy and you consider more "healthful." If you feel your diet is already balanced, describe how you accomplish your balanced intake and when you began eating this way.arrow_forwardWhich single food item contained you ate for the 3 days with the most sodium?arrow_forwardSelect a diet and choose one site that provides credible information. Explain why the source itself and/or the information on the site is credible. This should be a report. This site should be different from U.S News and World Report. For full credit, you must include the following information and elaborate in detail: The diet name The main components of the diet The credible website name and link What makes the credible website credible?arrow_forward
- Select a diet and give a summary of the main components. Do a web search of the diet and choose one link that provides misinformation. Explain why the site itself and/or the information on the site is not credible. This should be a report. This site should be different from U.S News and World Report. For full credit, you must include the following information and elaborate in detail: The diet name The main components of the diet The misinformation website and link What misinformation is being provided in the other website and how did you determine it was not credible?arrow_forward1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.arrow_forward2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0 Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…arrow_forward
- The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?arrow_forwardView History Bookmarks Window Help Quarter cements ents ons (17) YouTube Which amino acids would you expect to find marked on the alpha helix? canvas.ucsc.edu ucsc Complaint and Grievance Process - Academic Personnel pach orations | | | | | | | | | | | | | | | | 000000 000000000 | | | | | | | | | | | | | | | | | | | | | | 00000000 scope vious De 48 12.415 KATPM FEB 3 F1 F2 80 F3 a F4 F5 2 # 3 $ 85 % tv N A の Mon Feb 3 10:24 PM Lipid bilayer Submit Assignment Next > ZOOM < Å DII 8 བ བ F6 16 F7 F8 F9 F10 34 F11 F12 & * ( 6 7 8 9 0 + 11 WERTY U { 0 } P deletearrow_forwardDifferent species or organisms research for ecologyarrow_forward
- What is the result of the following gram stain: positive ○ capsulated ○ acid-fast ○ negativearrow_forwardWhat type of stain is the image below: capsule stain endospore stain gram stain negative stain ASM MicrobeLibrary.org Keplingerarrow_forwardWhat is the result of the acid-fast stain below: Stock Images by Getty Images by Getty Images by Getty Images by Getty Image Getty Images St Soy Getty Images by Getty Images by Getty Images Joy Getty encapsulated O endosporulating negative ○ positivearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Understanding Health Insurance: A Guide to Billin...Health & NutritionISBN:9781337679480Author:GREENPublisher:Cengage
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Understanding Health Insurance: A Guide to Billin...
Health & Nutrition
ISBN:9781337679480
Author:GREEN
Publisher:Cengage
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Nervous System - Get to know our nervous system a bit closer, how does it works? | Neurology; Author: FreeMedEducation;https://www.youtube.com/watch?v=6O-0CVAgaEM;License: Standard youtube license