ANATOMY AND PHYSIOLOGY ONLINE MATERIALS,
4th Edition
ISBN: 9781265761493
Author: McKinley
Publisher: MCG
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Chapter 16.4, Problem 18WDYL
Summary Introduction
To describe:
When an object is placed closer than 20 feet, then how the light is focused on the retina.
Concept introduction:
When an individual sees an object, then the processes are totally dependent on the distance of placing of an object. The cornea is very important in focusing of light. In medical science, 20 feet distance is kept standard to check the eyesight of an individual
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 16 Solutions
ANATOMY AND PHYSIOLOGY ONLINE MATERIALS,
Ch. 16.1 - How does a sensory receptor function as a...Ch. 16.1 - Prob. 2WDYLCh. 16.1 - Prob. 3WDYLCh. 16.1 - Prob. 4WDYLCh. 16.2 - What are the three types of unencapsulated tactile...Ch. 16.2 - Prob. 6WDYLCh. 16.2 - Prob. 7WDYLCh. 16.3 - What is the role of the mucus in detection of...Ch. 16.3 - Prob. 9WDYLCh. 16.3 - Prob. 10WDYL
Ch. 16.3 - Prob. 11WDYLCh. 16.4 - Prob. 12WDYLCh. 16.4 - Prob. 13WDYLCh. 16.4 - What are the three eye tunics; what is the primary...Ch. 16.4 - Compare the anatomic structure of the cornea and...Ch. 16.4 - Prob. 16WDYLCh. 16.4 - Prob. 17WDYLCh. 16.4 - Prob. 18WDYLCh. 16.4 - What are the differences between rods and cones...Ch. 16.4 - How does dark adaptation differ from light...Ch. 16.4 - What occurs during phototransduction of light?Ch. 16.4 - Prob. 22WDYLCh. 16.4 - Prob. 23WDYLCh. 16.5 - Prob. 24WDYLCh. 16.5 - Prob. 25WDYLCh. 16.5 - Prob. 26WDYLCh. 16.5 - What are the steps for detecting sounds?Ch. 16.5 - Compare the difference in how we perceive pitch...Ch. 16.5 - Prob. 29WDYLCh. 16.5 - Prob. 30WDYLCh. 16.5 - Prob. 31WDYLCh. 16 - _____ 1. Unencapsulated, terminal endings of...Ch. 16 - _____ 2. Each of these sensory receptors is...Ch. 16 - Prob. 3DYKBCh. 16 - Prob. 4DYKBCh. 16 - Prob. 5DYKBCh. 16 - Prob. 6DYKBCh. 16 - _____ 7. Which ear structure is correctly matched...Ch. 16 - Prob. 8DYKBCh. 16 - Prob. 9DYKBCh. 16 - Prob. 10DYKBCh. 16 - Prob. 11DYKBCh. 16 - Prob. 12DYKBCh. 16 - Prob. 13DYKBCh. 16 - Prob. 14DYKBCh. 16 - Prob. 15DYKBCh. 16 - Prob. 16DYKBCh. 16 - Prob. 17DYKBCh. 16 - Prob. 18DYKBCh. 16 - Describe the pathway by which sound waves enter...Ch. 16 - Explain how the vestibule and semicircular canals...Ch. 16 - Prob. 1CALCh. 16 - Prob. 2CALCh. 16 - Prob. 3CALCh. 16 - Prob. 4CALCh. 16 - Prob. 5CALCh. 16 - Prob. 1CSLCh. 16 - Prob. 2CSLCh. 16 - Prob. 3CSL
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