LIFE: THE SCIENCE OF BIOLOGY
LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 9781319145125
Author: Sadava
Publisher: MAC HIGHER
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Chapter 16.2, Problem 3R
Summary Introduction

To review:

The way, in which more than one gene at a time is regulated in eukaryotes.

Introduction:

Gene regulation is mainly controlled by the transcription factors (TFs). These factors attached to the ribonucleic acid (RNA) polymerase on the deoxyribonucleic acid (DNA) sequences and help to initiate or repress the gene transcription. Some of these factors can control multiple genes at a time if there is more than one copy of the binding sites for the transcription factor present on the sequence or on the operon.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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