Essential Cell Biology 5e
Essential Cell Biology 5e
5th Edition
ISBN: 9780393691108
Author: Bruce Alberts, Karen Hopkin, Alexander D Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Wa
Publisher: W. W. Norton
bartleby

Videos

Question
Book Icon
Chapter 16, Problem 7Q
Summary Introduction

To explain: The possibility of activation of the RTK when it is exposed to the antibodies which bind to the respective RTK.

Concept introduction: Receptor Tyrosine Kinases (RTK) are a unique group of receptors found on the membrane which have a kinase domain in them to phosphorylate the necessary target proteins (receptors also) to initiate the cascade. The kinase activity is activated only when the RTK receptor is in its dimer form. This acts as a check point to keep the initiation of cascade under check. The antibodies are proteins that identify a protein with their unique antigen binding site produced by the plasma cells. The antibodies are used by the plasma cells to defend against the invading pathogen. The same is exploited by the researchers to tag a protein to isolate the target protein of interest.

Summary Introduction

To explain: The effect of antibody binding to GPCR.

Concept introduction: Receptor Tyrosine Kinases (RTK) are a unique group of receptors found on the membrane which have a kinase domain in them to phosphorylate the necessary target proteins (receptors also) to initiate the cascade. The kinase activity is activated only when the RTK receptor is in its dimer form. This acts as a check point to keep the initiation of cascade under check. The antibodies are proteins that identify a protein with their unique antigen binding site produced by the plasma cells. The antibodies are used by the plasma cells to defend against the invading pathogen. The same is exploited by the researchers to tag a protein to isolate the target protein of interest.

Blurred answer
Students have asked these similar questions
Skip to main content   close Homework Help is Here – Start Your Trial Now! arrow_forward search SEARCH   ASK Human Anatomy & Physiology (11th Edition)BUY Human Anatomy & Physiology (11th Edition) 11th Edition ISBN: 9780134580999 Author: Elaine N. Marieb, Katja N. Hoehn Publisher: PEARSON   1 The Human Body: An Orientation expand_moreChapter 1 : The Human Body: An Orientation   Chapter Questions expand_moreSection: Chapter Questions   Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,... format_list_bulletedProblem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,... See similar textbooks Bartleby Related Questions Icon Related questions Bartleby Expand Icon bartleby Concept explainers bartleby Question Draw a replication bubble with two replication forks.blue lines are DNA single strands and red lines are RNA single strands.indicate all 3' and 5’ ends on all DNA single…
Provide an  answer
Question 4 1 pts Which of the following would be most helpful for demonstrating alternative splicing for a new organism? ○ its proteome and its transcriptome only its transcriptome only its genome its proteome and its genome
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Text book image
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Text book image
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Text book image
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Text book image
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Phlebotomy: Venipuncture Procedure; Author: Medical Lab Lady Gill;https://www.youtube.com/watch?v=LC9LABPts7M;License: Standard Youtube License