Chapter 16, Problem 2TMW

Summary Introduction

To explain:

The reason exogenous peptides processed in vesicles instead of in endoplasmic reticulum, as endogenous epitopes.

Introduction:

Processing of the peptides takes place inside the endoplasmic reticulum of the infected and antigen presenting cells which breaks the peptides into various smaller proteins. Degradation of antigenic peptides takes place in the proteosome complex to form smaller fragments.