Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 16, Problem 20P

Reciprocal crosses were performed using two inbred strains of mice, AKR and PWD, that have different alleles of many polymorphic loci. In each of the two crosses, placental tissue was isolated whose origin was strictly from the fetus (this can be separated by dissection from placental tissue originating from the mother). RNA was prepared from the fetal placental tissue and then subjected to “deep sequencing” (that is, RNA-Seq). Because of the polymorphisms, investigators could compare the number of “reads” of mRNAs for specific genes that were transcribed from maternal or paternal alleles, as shown in the following figure. (The x-axis shows the percentage of reads for the given mRNA that correspond to the AKR allele of that gene.)

Chapter 16, Problem 20P, Reciprocal crosses were performed using two inbred strains of mice, AKR and PWD, that have different

a. Which of the genes (A, B, or C) is maternally imprinted? Which is paternally imprinted? Which is not imprinted?
b. Why was it important to perform reciprocal crosses to determine whether any of the genes were imprinted?
c. Using the same type of diagram that indicates the percentage of AKR alleles, diagram the expected results for these same three genes if a female F mouse from the cross on the left (that is, a daughter of a cross between an AKR female and a PWD male) was then crossed to a PWD male. Describe the two possible outcomes for each gene.
Blurred answer
Students have asked these similar questions
The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
QUESTION 27 Label the structures marked A, B, C and explain the role of structure A. W plasma membrane For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). BIUS ☐ Paragraph Π " ΩΘΗ Β Open Sans, a... 10pt EE
examples of synamptomorphy

Chapter 16 Solutions

Genetics: From Genes to Genomes, 5th edition

Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Case Studies In Health Information Management
Biology
ISBN:9781337676908
Author:SCHNERING
Publisher:Cengage
Text book image
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Text book image
Essentials Health Info Management Principles/Prac...
Health & Nutrition
ISBN:9780357191651
Author:Bowie
Publisher:Cengage
Text book image
Basic Clinical Laboratory Techniques 6E
Biology
ISBN:9781133893943
Author:ESTRIDGE
Publisher:Cengage
Text book image
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License