Concept explainers
To describe: One observation in the human pedigree that rules out a recessive pattern of inheritance.
Introduction: Genetic disorder are caused due to abnormalities in the genome of a person and these disorders are inheritable from the parents to the offspring. Genetic disorders are of different types depending on the location of the infected genes and the type of allele on the chromosome such as autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked and mitochondrial disorders. For understanding the inheritance of human genetic diseases “pedigree analysis” is considered the most effective tool and it follows simple Mendelian pattern.
To describe: One observation in the human pedigree that rules out a dominant pattern of inheritance.
Introduction: The dominant and recessive pattern of inheritance is observed using the pedigree analysis. For a dominant pattern to be inherited only one of the dominant alleles need to be transferred but the recessive pattern of inheritance requires both the alleles that are transferred to be recessive.
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