Mutations are often considered harmful. Give an example of a mutation that would be beneficial to a microorganism. What gene would bear the mutation? How would the mutation alter the gene’s role in the cell, and what conditions would select for this mutant allele?

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Answer 1

Textbook Question

Chapter 16, Problem 1CHI

Mutations are often considered harmful. Give an example of a mutation that would be beneficial to a microorganism. What gene would bear the mutation? How would the mutation alter the gene’s role in the cell, and what conditions would select for this mutant allele?

Expert Solution

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Expert Solution

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

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Answer 2

Textbook Question

Chapter 16, Problem 1CHI

Mutations are often considered harmful. Give an example of a mutation that would be beneficial to a microorganism. What gene would bear the mutation? How would the mutation alter the gene’s role in the cell, and what conditions would select for this mutant allele?

Expert Solution

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Expert Solution

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

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Answer 3

Textbook Question

Chapter 16, Problem 1CHI

Mutations are often considered harmful. Give an example of a mutation that would be beneficial to a microorganism. What gene would bear the mutation? How would the mutation alter the gene’s role in the cell, and what conditions would select for this mutant allele?

Expert Solution

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Expert Solution

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

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Answer 4

Textbook Question

Chapter 16, Problem 1CHI

Mutations are often considered harmful. Give an example of a mutation that would be beneficial to a microorganism. What gene would bear the mutation? How would the mutation alter the gene’s role in the cell, and what conditions would select for this mutant allele?

Expert Solution

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Expert Solution

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

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Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Expert Solution

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

Answer 8

Expert Solution

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Answer 9

Expert Solution

Answer 10

Expert Solution

Answer 11

Expert Solution

Answer 12

Summary Introduction

To identify: The gene that bears the mutation with an example of the mutation that is beneficial to the micro-organism.

Introduction: Alteration in the DNA sequence of the cell is known as a mutation. Various types of mutations found in the cell. Some mutations arise due to changes in the single base pair of nucleotides and the addition or deletion of a single nucleotide pair in the exon of the DNA sequence. These kinds of small changes are known as point mutations, which are associated with only a single base pair in a particular site of the DNA sequence. Larger mutations in the DNA sequence are less common. The larger mutations are larger insertions, deletions, duplications, translocations, and inversions of nucleotide sequences. Mutations often occur in two ways such as spontaneous mutations (which arise occasionally) and induced mutations (which arise from the exposure of mutagens).

Answer 13

Explanation of Solution

Generally, mutations are harmful to the cell because they affect proteins and phenotype of an organism. However, some mutations play a beneficial effect on microorganisms, for instance,mutation-induced antibiotic resistance in microorganisms. For example, a mutation in the rpsL gene induces resistance to the streptomycin (an antibiotic).

Answer 14

Expert Solution

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

Answer 15

Expert Solution

Answer 16

Expert Solution

Answer 17

Expert Solution

Answer 18

Summary Introduction

To describe: The condition that selects the mutant allele and how these mutations alter the gene’s role in the cell.

Answer 19

Explanation of Solution

The rpsL is considered as an important part of the ribosome. The interaction of streptomycin with the small subunit of the ribosome inhibits translation in microorganisms. Hence, mutations in the rpsL can reduce the binding efficiency of the ribosome to streptomycin. Therefore, the environment containing lethal concentrations of antibiotic streptomycin could be a very strong selective pressure for a mutation. Though the rpsL gene mutation produces a beneficial effect by inducing streptomycin resistance, it may affect other cellular function and protein synthesis.

Answer 20

Ch. 16.1 - Retrieve, Infer, Apply List three ways in which...Ch. 16.1 - Compare and contrast the means by which the...Ch. 16.1 - Give examples of intragenic and extragenic...Ch. 16.1 - Retrieve, Infer, Apply Sometimes a point mutation...Ch. 16.1 - Retrieve, Infer, Apply Why might a missense...Ch. 16.2 - How would you screen for a tryptophan auxotroph?...Ch. 16.2 - Why is a small amount of histidine added to the...Ch. 16.2 - Retrieve, Infer, Apply Describe how replica...Ch. 16.2 - Retrieve, Infer, Apply Why are mutant selection...Ch. 16.2 - Retrieve, Infer, Apply Briefly discuss how...

Mutations are often considered harmful. Give an example of a mutation that would be beneficial to a microorganism. What gene would bear the mutation? How would the mutation alter the gene’s role in the cell, and what conditions would select for this mutant allele?

Solution Summary: The author explains that mutations occur due to changes in the single base pair of nucleotides and the addition or deletion of a single exon of the DNA sequence. Mutation-induced antibiotic resistance in microorganism

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