EBK BIOLOGY
EBK BIOLOGY
10th Edition
ISBN: 8220100474729
Author: Martin
Publisher: Cengage Learning US
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Chapter 16, Problem 16TYU
Summary Introduction

To estimate: The age at which half of individuals carrying a Huntington’s disease allele will develop symptoms.

Introduction: Huntington’s disease (HD) is a genetic disorder which causes progressive degeneration of nerve cells in the brain. It impairs the cognitive and functional abilities of a person. HD occurs due to an increase in the CAG trinucleotide repeats in the HD gene. It follows autosomal dominant inheritance pattern. An affected individual inherits the mutated gene from one of the affected parents. Every child with an affected parent has 50% chance of getting HD. The usual age of onset is 30-50 years.

Summary Introduction

To estimate: The age at which three-fourths of the individuals carrying a Huntington’s disease allele have developed symptoms.

Introduction: Huntington’s disease (HD) is a genetic disorder which causes progressive degeneration of nerve cells in the brain. It impairs the cognitive and functional abilities of a person. HD occurs due to an increase in the CAG trinucleotide repeats in the HD gene. It follows autosomal dominant inheritance pattern. An affected individual inherits the mutated gene from one of the affected parents. Every child with an affected parent has 50% chance of getting HD. The usual age of onset is 30-50 years.

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Linkage in common bean Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible.  Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population…
Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible.  Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…
can you help? I think its B but not sure

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