Concept explainers
(a)
Interpretation:
Procaine was one of the first local anesthetics. Its hydrochloride salt is marketed as Novocain.
If procaine is chiral or not and if it contains any stereocenter should be identified.
Concept Introduction:
Procaine contains amino ester group, it is a local anesthetic drug. It is required to relief the pain caused by injection of penicillin. It is also required in dentistry. In some regions, procaine is popular as Novocain.
(b)
Interpretation:
The nitrogen atom of procaine which is a stronger base should be identified.
Concept Introduction:
Procaine contains amino ester group, it is a local anesthetic drug. It is required to relief the pain caused by injection of penicillin. It is also required in dentistry. In some regions, procaine is popular as Novocain.
(c)
Interpretation:
A structural formula for the salt formed by treating procaine with one mole of HCl, showing which nitrogen is protonated and bears the positive charge should be determined.
Concept Introduction:
Procaine contains amino ester group, it is a local anesthetic drug. It is required to relief the pain caused by injection of penicillin. It is also required in dentistry. In some regions, procaine is popular as Novocain.
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Chapter 16 Solutions
Student Solutions Manual for Bettelheim/Brown/Campbell/Farrell/Torres' Introduction to General, Organic and Biochemistry, 11th
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- The pkb of methylamine, CH3NH2, is 3.36. Calculate the pka of its conjugate acid, CH3NH3*. pka =arrow_forwardWhy is H2SeO4 a weak acidarrow_forwardThe pKa of ascorbic acid (vitamin C, page 55) is 4.17, showing that it is slightly more acidic than acetic acid (CH3COOH, pKa 4.74). Show the four different conjugate bases that would be formed by deprotonation of the four different OH groups in ascorbic acid.arrow_forward
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