Essential Cell Biology (Fourth Edition)
Essential Cell Biology (Fourth Edition)
4th Edition
ISBN: 9780815345251
Author: Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D. Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 16, Problem 11Q

A.

Summary Introduction

To explain: The extracellular signal molecule acetylcholine has different effects on different cell types in an animal and often binds to different cell-surface receptor molecules on different cell types.

B.

Summary Introduction

To explain: After acetylcholine is secreted from cells, it is long-lived, because it has to reach target cells all over the body.

C.

Summary Introduction

To explain: How both the GTP-bound α subunits and nucleotide-free βγ complexes-but not GDP-bound, fully assembled G proteins can activate other molecules downstream of GPCRs.

D.

Summary Introduction

To explain: IP3 is produced directly by the cleavage of an inositol phospholipid, without the incorporation of an additional phosphate group.

E.

Summary Introduction

To explain: Calmodulin regulates the intracellular Ca2+ concentration.

F.

Summary Introduction

To explain:  Different signals originating from the plasma membrane can be integrated by cross-talk between different signaling pathways inside the cell.

G.

Summary Introduction

To explain: Tyrosine phosphorylation serves to build binding sites for other proteins to bind to RTKs.

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