BIO 117/118-LAB MANUAL>CUSTOM<
15th Edition
ISBN: 9781307026757
Author: Mader
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Question
Chapter 15.3, Problem 1CYP
Summary Introduction
To write:
The essential role of hemoglobin (Hb) in carrying oxygen, carbon dioxide, and hydrogen ions.
Given:
The hemoglobin is responsible for transport of oxygen and carbon dioxide throughout the body with the help of hydrogen ions.
Introduction:
The hemoglobin is the globin protein present on the surface of red blood cells. The hemoglobin helps in binding and transport of oxygen and carbon dioxide molecules in the body. The hydrogen ions help in maintaining the buffer level in the blood plasma for gaseous exchange.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 15 Solutions
BIO 117/118-LAB MANUAL>CUSTOM<
Ch. 15.1 - Summarize the major functions of the respiratory...Ch. 15.1 - Trace the path of air from the human nose to the...Ch. 15.1 - Prob. 3LOCh. 15.1 - Prob. 1CYPCh. 15.1 - Discuss the arrangement of the trachea, esophagus,...Ch. 15.1 - Prob. 3CYPCh. 15.1 - Prob. 4CYPCh. 15.1 - Prob. 1ACh. 15.1 - Prob. 2ACh. 15.2 - Prob. 1LO
Ch. 15.2 - Contrast the mechanisms of inspiration and...Ch. 15.2 - Prob. 3LOCh. 15.2 - Prob. 1CYPCh. 15.2 - Prob. 2CYPCh. 15.2 - Prob. 3CYPCh. 15.2 - Prob. 3ACh. 15.2 - Prob. 4ACh. 15.2 - Prob. 5ACh. 15.3 - Distinguish between external and internal...Ch. 15.3 - Prob. 2LOCh. 15.3 - Prob. 3LOCh. 15.3 - With regard to producing tissue-engineered human...Ch. 15.3 - Prob. 2QTCCh. 15.3 - Prob. 3QTCCh. 15.3 - Prob. 1CYPCh. 15.3 - Prob. 2CYPCh. 15.3 - Describe why the process of respiration is said to...Ch. 15.3 - Prob. 6ACh. 15.3 - Prob. 7ACh. 15.3 - The binding of small amounts of carbon dioxide to...Ch. 15.4 - Prob. 1LOCh. 15.4 - Prob. 2LOCh. 15.4 - Prob. 1QTCCh. 15.4 - Prob. 2QTCCh. 15.4 - Prob. 1AQTCCh. 15.4 - Why does cigarette smoke have a negative effect on...Ch. 15.4 - Prob. 1CYPCh. 15.4 - Prob. 2CYPCh. 15.4 - Prob. 3CYPCh. 15.4 - Prob. 9ACh. 15.4 - Prob. 10ACh. 15.4 - Prob. 11ACh. 15 - Prob. S7.1BYBCh. 15 - Prob. S11.5BYBCh. 15 - Prob. S12.4BYBCh. 15 - Prob. 1CSCh. 15 - Prob. 2CSCh. 15 - Prob. 3CSCh. 15 - Prob. 1TCCh. 15 - Prob. 2TCCh. 15 - Prob. 3TCCh. 15 - Prob. 4TC
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