EBK HUMAN PHYSIOLOGY
15th Edition
ISBN: 9781260163049
Author: Fox
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 15, Problem 8bCP
Summary Introduction
To review:
The graphical representation of primary and secondary immune response and their characteristics.
Introduction:
The body is protected from disease causing organisms or molecules by the immune system of the body. The immune system provides two types of immunity, firstly, the innate immunity which is already present since birth and is non-specific type providing the first line defense mechanism. The second one is adaptive immunity that is built through the exposure of foreign bodies and it is antigen specific. The latter acts as a second line of defense.
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A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?
The cell membranes are more resistant than normal.
An isotonic solution had been added instead of water.
A solution of 0.1 M NaCl had been added instead of water.
Not enough water had been added to the red blood cell pellet.
The man had sickle-cell anaemia.
A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?
The cell membranes are more resistant than normal.
An isotonic solution had been added instead of water.
A solution of 0.1 M NaCl had been added instead of water.
Not enough water had been added to the red blood cell pellet.
The man had sickle-cell anaemia.
With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin
Chapter 15 Solutions
EBK HUMAN PHYSIOLOGY
Ch. 15 - List the phagocytic cells found in blood and...Ch. 15 - Prob. 1bCPCh. 15 - Prob. 2aCPCh. 15 - Prob. 2bCPCh. 15 - Prob. 2cCPCh. 15 - Prob. 3CPCh. 15 - Prob. 4aCPCh. 15 - Prob. 4bCPCh. 15 - Prob. 5CPCh. 15 - Prob. 6aCP
Ch. 15 - Prob. 6bCPCh. 15 - Define the term histocompatibility antigens and...Ch. 15 - Prob. 7bCPCh. 15 - Prob. 8aCPCh. 15 - Prob. 8bCPCh. 15 - Prob. 8cCPCh. 15 - Prob. 8dCPCh. 15 - Prob. 9CPCh. 15 - Prob. 10aCPCh. 15 - Prob. 10bCPCh. 15 - Prob. 10cCPCh. 15 - Prob. 11CPCh. 15 - Prob. 12aCPCh. 15 - Prob. 12bCPCh. 15 - Which of these offers a nonspecific defense...Ch. 15 - Prob. 2RACh. 15 - Prob. 3RACh. 15 - Prob. 4RACh. 15 - Prob. 5RACh. 15 - Prob. 6RACh. 15 - Prob. 7RACh. 15 - Mast cell secretion during an immediate...Ch. 15 - Prob. 9RACh. 15 - Which of these cell types aids the activation of T...Ch. 15 - Prob. 11RACh. 15 - Delayed hypersensitivity is mediated by...Ch. 15 - Active immunity may be produced by...Ch. 15 - Which of these statements about class-2 MHC...Ch. 15 - Prob. 15RACh. 15 - Prob. 16RACh. 15 - Prob. 17RACh. 15 - Which of these statements about gamma interferon...Ch. 15 - Explain how antibodies help to destroy invading...Ch. 15 - Identify the different types of interferons and...Ch. 15 - Distinguish between the class-I and class-2 MHC...Ch. 15 - Prob. 22RACh. 15 - Prob. 23RACh. 15 - Describe how plasma cells attack antigens and how...Ch. 15 - Explain how tolerance to self-antigens may be...Ch. 15 - Use the clonal selection theory to explain how...Ch. 15 - Prob. 27RACh. 15 - Distinguish between immediate and delayed...Ch. 15 - Describe regulatory T lymphocytes and their...Ch. 15 - Prob. 30RACh. 15 - The specific T lymphocyte immune response is...Ch. 15 - Lizards are cold-blooded; their body temperature...Ch. 15 - Why are antibodies composed of different chains,...Ch. 15 - As a scientist trying to cure allergy, you are...Ch. 15 - The part of the placenta that invades the mother's...Ch. 15 - Describe the antigen-dependent and...Ch. 15 - People with peanut allergies could go into...Ch. 15 - Identify some immunologically privileged sites in...Ch. 15 - Use figure 15.6 to answer the following questions...Ch. 15 - Use figure 15.6 to answer the following questions...Ch. 15 - Prob. 41RACh. 15 - Prob. 42RA
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- With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobinarrow_forwardWhich ONE of the following is FALSE regarding haemoglobin? It has two alpha subunits and two beta subunits. The subunits are joined by disulphide bonds. Each subunit covalently binds a haem group. Conformational change in one subunit can be transmitted to another. There are many variant ("mutant") forms of haemoglobin that are not harmful.arrow_forwardWhich ONE of the following is FALSE regarding haemoglobin? It has two alpha subunits and two beta subunits. The subunits are joined by disulphide bonds. Each subunit covalently binds a haem group. Conformational change in one subunit can be transmitted to another. There are many variant ("mutant") forms of haemoglobin that are not harmful.arrow_forward
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Immune System and Immune Response Animation; Author: Medical Sciences Animations;https://www.youtube.com/watch?v=JDdbUBXPKc4;License: Standard YouTube License, CC-BY
Immune response: summary; Author: Dr Bhavsar Biology;https://www.youtube.com/watch?v=ADANgHkX4OY;License: Standard Youtube License