Concepts of Genetics (11th Edition)
Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 15, Problem 5PDQ
Summary Introduction

To determine: The reason behind considering mutations important for the process of evolution if they are thought to be deleterious.

Introduction: Mutation is defined as any change in the nucleotide sequence that alters the phenotype of the organism. A base-pair change in any part of a DNA molecule can be considered as a mutation. It comprises either a substitution in the single base-pair, deletion or insertion of one or more base pairs, or a major alteration in the structure of a chromosome.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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Please finish the chart at the bottom. Some of the answers have been filled in.

Chapter 15 Solutions

Concepts of Genetics (11th Edition)

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY