Campbell Biology in Focus; Modified Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780134433776
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman
Publisher: PEARSON
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Textbook Question
Chapter 15, Problem 3TYU
Which of the following is an example of post-transcriptional control of gene expression?
- A. the addition of methyl groups to cytosine bases of DNA
- B. the binding of transcription factors to a promoter
- C. the removal of introns and alternative splicing of exons
- D. the binding of RNA polymerase to transcription factors
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Transcriptional repressor proteins (e.g., lac repressor), antisense RNA, and feedback inhibition are three different mechanisms that turn off the expression of genes and gene products. Which of these three mechanisms will be most effective in each of the following situations?
A. Shutting down the synthesis of a polypeptide
B. Shutting down the synthesis of mRNA
C. Shutting off the function of a protein For your answers to parts A–C that list more than one mechanism, which mechanism will be the fastest or the most efficient?
Which statement/s is/are TRUE about transcription?A. During transcription, DNA polymerase binds to RNA and separates the DNA strands.B. RNA polymerase uses one strand of DNA as a template to assemble nucleotides into a strand of RNA.C. RNA polymerase binds only to DNA promoters, which have specific base sequences.D. Promoters are signals in RNA that indicate to RNA polymerase where to begin transcription.E. Transcription occurs in the 3’ to 5’ direction with respect to the growing mRNA strand.
A transcription factor (protein - orange/green) is bound to a promoter of a gene (DNA - blue) it regulates. What changes would result in the gene not being expressed?
A. Mutations in the DNA sequence where the TF is bound
B. Mutations in the DNA binding domain of the TF
C. Mutations in the 3’UTR (untranslated region) of this gene
A and B only
B and C only
A, B, and C
Chapter 15 Solutions
Campbell Biology in Focus; Modified Mastering Biology with Pearson eText -- ValuePack Access Card -- for Campbell Biology in Focus (2nd Edition)
Ch. 15.1 - How does binding of the trp corepressor to its...Ch. 15.1 - Describe the binding of RNA polymerase,...Ch. 15.1 - WHAT IF? A certain mutation in E. coli changes the...Ch. 15.2 - Prob. 1CCCh. 15.2 - Compare the roles of general and specific...Ch. 15.2 - Prob. 3CCCh. 15.3 - WHAT IF? Suppose the mRNA being degraded in Figure...Ch. 15.3 - MAKE CONNECTIONS Inactivation of one of the X...Ch. 15.4 - Describe the role of complementary base pairing...Ch. 15.4 - WHAT IF? Study the microarray in Figure 15.17. If...
Ch. 15 - If a particular operon encodes enzymes for making...Ch. 15 - The functioning of enhancers is an example of A. a...Ch. 15 - Which of the following is an example of...Ch. 15 - Prob. 4TYUCh. 15 - Prob. 5TYUCh. 15 - Which of the following would not be true of cDNA...Ch. 15 - Prob. 7TYUCh. 15 - SCIENTIFIC INQUIRY Imagine you want to study one...Ch. 15 - FOCUS ON EVOLUTION DNA sequences can act as tape...Ch. 15 - FOCUS ON INTERACTIONS In a short essay (100150...Ch. 15 - Prob. 11TYU
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- Which of the following gene expression regulatory mechanisms saves the most energy but takes the longest to fully express the genes once signaled? a. transcriptional regulation b. post-transcriptional regulation c. post-translational regulation d. translational regulationarrow_forwardWhich of the following is true for both prokaryotic and eukaryotic gene expression? A. After transcription, a 3' poly-A tail and a 5' cap are added to MRNA. B. Translation of MRNA can begin before transcription is complete. C. RNA polymerase binds to the promoter region to begin transcription. D. MRNA is synthesized in the 3' → 5' direction.arrow_forwardFor each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosomearrow_forward
- Which of the following is not an example of constitutively expressed gene? a. genes for cell division and growth b. genes involved in DNA repair c. genes for cellular respiration d. genes that function in ATP synthesisarrow_forwardWhich of the following is not true regarding gene regulation that involves DNA bending? a. The precise distance between the regulatory sequence and the promoter is important. b. Effect can be to repress transcription c. Effect can be to activation transcription d. Regulated genes can be thousands of base pairs away from the regulatory sitesarrow_forwardWhich of the following will increase the rate of transcription? a. Activation of a transcriptional repressor b. Inhibition of a transcriptional activator c. Histone methylation leading to chromatin compaction d. Removal of RNA polymerasearrow_forward
- Which of the following may produce more than one functional protein from an mRNA transcript?a. chromatin condensation b. transcriptional regulation c. epigeneticsd. alternative mRNA processingarrow_forwardDifferential RNA splicing may result in: a. A shift in the ratio of mRNA produced from two neighboring genes b. Inversion of exons in the mature mRNA c. Production of the same protein from two different genes d. Production of two different proteins with different properties from a single genearrow_forwardArrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forward
- Define and describe the roles of the following in transcription: a. transcription factors b. RNA polymerase c. promoter d. sigma factor e. enhancer f. TATA boxarrow_forwardHow would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicingarrow_forwardGenetic expression in general can be regulated at various stages. Identify specific processes that control gene expression at the: a. transcription level - b. post-transcription level - c. translation level -arrow_forward
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