Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 15, Problem 24ESP

Presented here are hypothetical findings from studies of hetero-karyons formed from seven human xeroderma pigmentosum cell strains:

Chapter 15, Problem 24ESP, Presented here are hypothetical findings from studies of hetero-karyons formed from seven human

Note: + = complementation; − = no complementation

These data are measurements of the occurrence or nonoccurrence of unscheduled DNA synthesis in the fused heterokaryon. None of the strains alone shows any unscheduled DNA synthesis. Which strains fall into the same complementation groups? How many different groups are revealed based on these data? What can we conclude about the genetic basis of XP from these data?

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