EBK BIOCHEMISTRY
6th Edition
ISBN: 9781337431200
Author: GRISHAM
Publisher: CENGAGE LEARNING - CONSIGNMENT
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Chapter 15, Problem 21P
Interpretation Introduction
To Suggest:
Reactions by which the reversibility of glycogen phosphorylate from a form to b form when hormone disappears should be suggested.
Introduction:
Glycogen phosphorylase has two forms as less active b form and more active a form. Glycogen phosphorylase can be activated via an enzyme cascade. First adenylyl cyclase which is a membrane bound enzyme that converts ATP to cAMP, is stimulated by a hormone. cAMP is a signaling molecule found in all eukaryotic cells. Cyclic AMP activates cAMP dependent protein kinase and induces a conformational change. This activated cAMP protein kinase can phosphorylate other proteins like phosphorylase kinase. Phosphorylase kinase is inactive in unphosphorylated state and active in phosphorylated form. The activated phosphorylase kinase, then phosporylates glycogen phosphorylase. This results in the conversion of less active glycogen phosphorylase form b into more active form a.
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9. Which one of the compounds below is the major organic product obtained from
the following reaction sequence, starting with ethyl acetoacetate?
요요.
1. NaOCH2CH3
CH3CH2OH
1. NaOH, H₂O
2. H3O+
3. A
OCH2CH3
2.
ethyl acetoacetate
ii
A
3. H3O+
OH
B
C
D
E
7. Only one of the following ketones cannot be made via an acetoacetic ester
synthesis. Which one is it?
Ph
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A
B
C
D
E
2. Which one is the
major organic
product obtained
from the following
reaction sequence?
HO
A
OH
1. NaOEt, EtOH
1. LiAlH4
EtO
OEt
2. H3O+
2. H3O+
OH
B
OH
OH
C
-OH
HO
-OH
OH
D
E
.CO₂Et
Chapter 15 Solutions
EBK BIOCHEMISTRY
Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Prob. 5PCh. 15 - Prob. 6PCh. 15 - Prob. 7PCh. 15 - Prob. 8PCh. 15 - Answers to all problems are at the end of this...Ch. 15 - Answers to all problems are at the end of this...
Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Answers to all problems are at the end of this...Ch. 15 - Prob. 14PCh. 15 - Prob. 15PCh. 15 - Prob. 16PCh. 15 - Prob. 17PCh. 15 - Prob. 18PCh. 15 - Prob. 19PCh. 15 - Prob. 20PCh. 15 - Prob. 21PCh. 15 - Prob. 22PCh. 15 - Prob. 23PCh. 15 - Prob. 24P
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