BIOL:CONCEPT+INVEST.ETEXT
BIOL:CONCEPT+INVEST.ETEXT
5th Edition
ISBN: 9781264154173
Author: Hoefnagels
Publisher: MCG
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Chapter 14.6, Problem 5MC

How is a cladogram constructed?

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Patients with multiple sclerosis frequently suffer from blurred vision. Drug X was developed to reduce blurred vision in healthy patients, but the effectiveness had not been tested on those suffering from multiple sclerosis. A study was conducted to determine if Drug X is effective at reducing blurry vision in multiple sclerosis patients. To be considered effective, a drug must reduce blurred vision by more than 30% in patients. Researchers predicted that a 20 mg dose of the drug would be effective for treating blurred vision in multiple sclerosis patients by reducing blurred vision by more than 30%. Drug X was administered to groups of multiple sclerosis patients at three doses (10 mg/day, 20 mg/day, 30 mg/day) for three weeks. A fourth group of patients was given a placebo containing no drug X for the same length of time. Vision clarity was measured for each patient before and after the three-week period using a standard vision test. The results were analyzed and graphed (See Figure…
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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
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