Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Question
Chapter 14.4, Problem 2CC
Summary Introduction
To explain: The change in the single amino acid in hemoglobin that results in the aggregation of hemoglobin in long fibers.
Concept introduction:
The primary structure of proteins is the linear sequence of amino acids. It determines the shape and the functional ability of the protein. A small change in the amino acid sequence can alter a protein’s shape and its functions.
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What does the hemoglobin graph regarding YO2 represent?
4. You are to choose the members of an expedition that will climb several high mountains.
Each applicant for one of the positions is a heterozygote for an abnormal hemoglobin:
Person A: Hb Albany: a methionine has been substituted for Lys 82 in the B-subunit.
Person B: Hb Cowtown: a leucine has been substituted for His 146 in the B-subunit.
Person C: Hb Flagstaff: an isoleucine has been substituted for Val 1 in the B-subunit.
For the locations of the amino acid residues refer to your text, the figure on page 9 of this lab,
and the KING exercises. Assuming that each of these candidates is equal in ability at low
altitude, which one would you choose for the expedition? To answer this question, determine
how the substituted amino acid affects the structure and function of each abnormal
hemoglobin, and describe the physiological effect. Focus on the stabilization of the T versus
R state of hemoglobin, and the consequent physiological changes that might occur
altitude. Keep your answers…
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Chapter 14 Solutions
Campbell Biology (11th Edition)
Ch. 14.1 - DRAW IT Pea plants heterozygous for flower...Ch. 14.1 - WHAT IF? List all gametes that could be made by a...Ch. 14.1 - MAKE CONNECTIONS In some pea plant crosses, the...Ch. 14.2 - Prob. 1CCCh. 14.2 - Two organisms, with genotypcs BbDD and BBDd, are...Ch. 14.2 - WHAT IF? Three characters (flower color, seed...Ch. 14.3 - What two properties, one structural and one...Ch. 14.3 - If a man with type AB blood marries a woman with...Ch. 14.3 - WHAT IF? A rooster with gray feathers and a hen...Ch. 14.4 - Beth and Tom each have a sibling with cystic...
Ch. 14.4 - Prob. 2CCCh. 14.4 - Prob. 3CCCh. 14.4 - MAKE CONNECTIONS In Table 14.1, note the...Ch. 14 - When Mendel did crosses of true-breeding purple-...Ch. 14 - DRAW IT Redraw the Punnett Square on The right...Ch. 14 - Inheritance patterns are often more complex than...Ch. 14 - Both members of a couple know that they are...Ch. 14 - DRAW IT Two pea plants heterozygous for the...Ch. 14 - A man with type A blood marries a woman with type...Ch. 14 - A man has six fingers on each hand and six toes on...Ch. 14 - DRAW IT A pea plant heterozygous for inflated pods...Ch. 14 - Flower position, stem length, and seed shape are...Ch. 14 - Hemochromatosis is an inherited disease caused by...Ch. 14 - The genotype of F1, individuals in a tetrahybrid...Ch. 14 - What is the probability that each of thc following...Ch. 14 - Prob. 9TYUCh. 14 - Prob. 10TYUCh. 14 - In tigers, a recessive allele of a particular gene...Ch. 14 - In maize (com) plants,a dominant allele I inhibits...Ch. 14 - The pedigree belowtraces the inheritance of...Ch. 14 - Imagine that you are a genetic counselor, and a...Ch. 14 - EVOLUTION CONNECTION Over the past half century,...Ch. 14 - SCIENTIFIC INQUIRY You are handed a mystery pea...Ch. 14 - Prob. 17TYUCh. 14 - SYNTHESIZE YOUR KNOWLEDGE Just for fun, imagine...
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