FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
11th Edition
ISBN: 2818440070938
Author: Martini
Publisher: PEARSON C
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Chapter 14, Problem 8RQ
Summary Introduction

Introduction:

The blood brain barrier (BBB) is formed by the endothelial cells that are interconnected to each other by the tight junctions. This junction serves as a barrier against the entry of unwanted molecules inside the membrane of the blood vessels. The lipid membrane is permeable to the small ions like oxygen, carbon dioxide, ammonia, lipids, that can easily move across the bipolar lipid membrane and move into the interstitial fluid. The process of diffusion, active and passive transport moves the ions and water molecules across the membrane.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY

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