BIOL 107 LAB PKG W/LAB SG +ACCESS >IC<
BIOL 107 LAB PKG W/LAB SG +ACCESS >IC<
12th Edition
ISBN: 9781259827082
Author: Mader
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 14, Problem 1NS.2QC
Summary Introduction

To determine:

Why knowing which genes are active in which cells is important.

Introduction:

Every nucleated cell in a eukaryote contains the DNA. The DNA is composed of thousands of genes. However, every gene is not expressed in every cell of the body. Like the neurons will express genes that makes the neurotransmitter while hepatocytes will express genes that makes bile. Similarly, a cell expresses only those genes that it needs.

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a) What type of bond does helicase break? b) Which of these two types of bonds is stronger? c) Describe why it is necessary for the lagging strand to be made in fragments, called Okazaki fragments.
a) How are the model single nucleotides structurally different than real-life dNTPs? b)If you wanted to make these DNA nucleotides into RNA nucleotides, what could you do to them? c)Name the type of bond that is being formed by DNA Polymerase III.
You will be building a double-stranded DNA molecule, representing a short (20 base) sequence that could be found in a chromosome.  It will have a 3' --> 5' strand and a 5' --> 3' strand. Use two full 12-base-pair DNA models.  a) Upload a picture of your model reflecting the Initiation phase of DNA replication.  b) Upload a picture of your model once it has entered the Elongation phase of DNA replication, showing the action of Primase. c)Upload a picture of your model once it has entered the Elongation phase of DNA replication, showing the action of DNA Polymerase III.
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