BIOCHEMISTRY
8th Edition
ISBN: 9781319296186
Author: BERG
Publisher: MAC HIGHER
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Question
Chapter 14, Problem 14P
Interpretation Introduction
Interpretation:
Effect of overexpression of mutated EGFR on EGF signaling should be determined.
Concept introduction:
EGF (epidermal growth factor) is a peptide hormone, which is submaxillary glands of the humans. It is also found in the parotid gland and submandibular gland of the humans. EGF binds to the EGFR (epidermal growth factor receptor). The main functions of EGF are cell proliferation, differentiation, and survival.
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9. Which one of the compounds below is the major organic product obtained from
the following reaction sequence, starting with ethyl acetoacetate?
요요.
1. NaOCH2CH3
CH3CH2OH
1. NaOH, H₂O
2. H3O+
3. A
OCH2CH3
2.
ethyl acetoacetate
ii
A
3. H3O+
OH
B
C
D
E
7. Only one of the following ketones cannot be made via an acetoacetic ester
synthesis. Which one is it?
Ph
کہ
A
B
C
D
E
2. Which one is the
major organic
product obtained
from the following
reaction sequence?
HO
A
OH
1. NaOEt, EtOH
1. LiAlH4
EtO
OEt
2. H3O+
2. H3O+
OH
B
OH
OH
C
-OH
HO
-OH
OH
D
E
.CO₂Et
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