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Concept explainers
As shown in Figure 14.12, four regions within the trpL mRNA can form stem-loops. Let’s suppose that mutations have been previously identified that prevent the ability of a particular region to form a stem-loop with a complementary region. For example, a region 1 mutant cannot form a 1-2 stem-loop, but it can still form a 2-3 or 3-4 stem-loop. Likewise, a region 4 mutant can form a 1-2 or 2-3 stem-loop but not a 3-4 stem-loop. Under each of the following sets of conditions, would attenuation occur?
A. Region 1 is mutant, tryptophan is high, and translation is not occurring.
B. Region 2 is mutant, tryptophan is low, and translation is occurring.
C. Region 3 is mutant, tryptophan is high, and translation is not occurring.
D. Region 4 is mutant, tryptophan is low, and translation is not occurring.
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Chapter 14 Solutions
Genetics: Analysis and Principles
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- Answer iarrow_forwardAnswerarrow_forwardcalculate the questions showing the solution including variables,unit and equations all the questiosn below using the data a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forward
- QUESTION 8 For the following pedigree, assume that the mode of inheritance is X-linked recessive, and that the trait has full penetrance and expressivity and occurs at a very low frequency in the hum population. Using XA for the dominant allele and Xa for the recessive allele, assign genotypes for the following individuals (if it is not possible to figure out the second allele of a genotype, that with an underscore): 2 m 1 2 1 2 4 5 6 7 8 9 IV 1 2 3 5 6 7 8 CO 9 10 12 13 V 1, 2 3 4 5 6 7 8 9 10 11 12 13 a. Il-1: b. 11-2: c. III-3: d. III-4: e. If individuals IV-11 and IV-12 have another child, what is the probability that they will have a boy with the disorder?arrow_forwardAnswerrarrow_forwardplease,show workings ahd solutions calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forward
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