Human Biology
15th Edition
ISBN: 9781259689796
Author: Sylvia Mader, Michael Windelspecht
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 13.4, Problem 2LO
Summarize the causes of fibromyalgia, muscular dystrophy, myasthenia gravis, and muscle cancer.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Case Study—Ella
Review the case study and then answer Parts A through F.
Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch.
Categories of Sandwich Options (Top of the screen)
Breads
Spreads
Cheeses
Vegetables
Proteins
Specific food items to select
White Bread 6-inches
Honey Mustard
Provolone
LettuceTomatoBell Peppers
Turkey
Part A - Reading Nutrition Facts Panels for Total Kilocalories
How many total kilocalories are in Ella’s sandwich?
_____…
Chapter 13 Solutions
Human Biology
Ch. 13.1 - List the three types of muscles and provide a...Ch. 13.1 - Prob. 2LOCh. 13.1 - Prob. 3LOCh. 13.2 - Prob. 1LOCh. 13.2 - Prob. 2LOCh. 13.2 - Prob. 3LOCh. 13.2 - Prob. 1BTSCh. 13.2 - Prob. 2BTSCh. 13.3 - Prob. 1LOCh. 13.3 - Prob. 2LO
Ch. 13.3 - Prob. 3LOCh. 13.3 - Prob. 4LOCh. 13.3 - Prob. 1BTBCh. 13.3 - Prob. 2BTBCh. 13.3 - Prob. 1BTSCh. 13.3 - Prob. 2BTSCh. 13.4 - Prob. 1LOCh. 13.4 - Summarize the causes of fibromyalgia, muscular...Ch. 13.4 - Prob. 1BTHCh. 13.4 - Prob. 2BTHCh. 13.5 - Prob. 1LOCh. 13.5 - Prob. 2LOCh. 13 - Prob. 1ACh. 13 - Which of the following terms is not linked to its...Ch. 13 - Prob. 3ACh. 13 - Prob. 4ACh. 13 - Prob. 5ACh. 13 - Label each of the indicated items in the diagram...Ch. 13 - Prob. 7ACh. 13 - Prob. 8ACh. 13 - Prob. 9ACh. 13 - Prob. 10ACh. 13 - Prob. 11ACh. 13 - Prob. 12ACh. 13 - Prob. 1TCCh. 13 - Prob. 2TCCh. 13 - Prob. 3TC
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