<LCPO> BIOLOGY
<LCPO> BIOLOGY
12th Edition
ISBN: 9781266216398
Author: Raven
Publisher: MCG CUSTOM
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Chapter 13.3, Problem 1LO
Summary Introduction

To explain: The inheritance pattern for genes compacted in the DNA of mitochondrion and chloroplast.

Introduction: All eukaryotic organisms contain chromosomes, and the number of chromosomes varies in different organisms. In humans and several other species, diploid (2n) number of chromosomes is present. The diploid number of chromosomes indicates that each parent contributes equally to the offspring. Therefore for humans, the diploid and haploid number is 46 and 23, respectively. Of these, 22 pairs are perfectly similar in both females and males and are referred to as autosomes. The rest of the pair is referred to as sex chromosomes: XY in males and XX in females. Doubling of gene products (sex-linked) is ultimately prevented by dosage compensation

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY