NESTER'S MICROBIOLOGY-CONNECT >CUSTOM<
9th Edition
ISBN: 9781265432287
Author: Anderson
Publisher: MCG CUSTOM
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Chapter 13, Problem 6MC
Summary Introduction
Introduction:
Phages are the small entities, which cannot be classified in living and nonlivingcategories. Viruses infecting bacteria are called bacteriophages. Phages usually infect their host cell by two mechanisms, namely the lytic cycle and lysogenic cycle. Phages were classified on the basis of morphology and genetic material. Filamentous phages are the type of bacteriophages or viruses of bacteria, which have filamentous or rod-likeshape. Filamentousphages are the single-stranded DNA (deoxyribonucleic acid) containing phages, which usually infects Gram-negative bacteria.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 13 Solutions
NESTER'S MICROBIOLOGY-CONNECT >CUSTOM<
Ch. 13 - Prob. 1SACh. 13 -
2. How is the replication cycle of lambda phage...Ch. 13 -
3. What is lysogenic conversion?
Ch. 13 -
4. How is specialized transduction different from...Ch. 13 -
5. What is the difference between acute and...Ch. 13 -
6. Why must (–) strand but not (+) strand RNA...Ch. 13 - Why are RNA viruses and retroviruses more...Ch. 13 - What is the role of a prophage in persistent...Ch. 13 -
9. How do oncogenes differ from proto-oncogenes?
Ch. 13 - Describe how prions propagate.
Ch. 13 - Prob. 1MCCh. 13 - Prob. 2MCCh. 13 -
3. Classification of viruses is based on all of...Ch. 13 - Prob. 4MCCh. 13 -
5. All phages must be able to
1) inject their...Ch. 13 - Prob. 6MCCh. 13 -
7. Influenza vaccines must be changed yearly...Ch. 13 - Prob. 8MCCh. 13 - Prob. 9MCCh. 13 - Prob. 10MCCh. 13 -
1. A public health physician isolated large...Ch. 13 - Prob. 2ACh. 13 - Viruses that infect bacterial cells do not infect...Ch. 13 - Prob. 2CT
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