The way in which variable penetrance of the Diamond Blackfan Anemia (DBA) can help in studying the molecular events that cause the disorder. Introduction: DBA is classified as an autosomal dominant disorder that is caused by a mutation in one of the 11 genes that code for ribosomal proteins. An individual suffering from this disease is born with birth defects, bone marrow failure, and also has a tendency to develop cancer. Genetic disorders are caused by the abnormalities of the genome. These disorders are inherited as the genetic information from both the parents is passed down to the progeny. DBA is caused by a mutation in the genes that code for ribosomal protein. The symptoms of this disorder vary from individual to individual. Some of them include fast heartbeat, heart murmur, a pale skin, and birth defects, such as abnormality of the hands, heart, face, kidneys, head, or genital area.

Question

Want to see the full answer?

Answer 1

Question

Chapter 13, Problem 3CS

Summary Introduction

To review:

The way in which variable penetrance of the Diamond Blackfan Anemia (DBA) can help in studying the molecular events that cause the disorder.

Introduction:

DBA is classified as an autosomal dominant disorder that is caused by a mutation in one of the 11 genes that code for ribosomal proteins. An individual suffering from this disease is born with birth defects, bone marrow failure, and also has a tendency to develop cancer.

Genetic disorders are caused by the abnormalities of the genome. These disorders are inherited as the genetic information from both the parents is passed down to the progeny. DBA is caused by a mutation in the genes that code for ribosomal protein. The symptoms of this disorder vary from individual to individual. Some of them include fast heartbeat, heart murmur, a pale skin, and birth defects, such as abnormality of the hands, heart, face, kidneys, head, or genital area.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Normal dive (for diving humans) normal breathing dive normal breathing Oz level CO2 level urgent need to breathe Oz blackout zone high CO2 triggers breathing 6. This diagram shows rates of oxygen depletion and carbon dioxide accumulation in the blood in relation to the levels needed to maintain consciousness and trigger the urgent need to breathe in diving humans. How might the location and slope of the O₂ line differ for diving marine mammals such as whales and dolphins? • How might the location and slope of the CO₂ line differ for diving marine mammals such as whales and dolphins? • • Draw in predicted lines for O2 and CO2, based on your reasoning above. How might the location of the Urgent Need to Breathe line and the O2 Blackout Zone line differ for diving marine mammals? What physiological mechanisms account for each of these differences, resulting in the ability of marine mammals to stay submerged for long periods of time?

foraging/diet type teeth tongue stomach intestines cecum Insectivory numerous, spiky, incisors procumbentExample: moleExample: shrew -- simple short mostly lacking Myrmecophagy absent or reduced in numbers, peg-likeExample: tamandua anteater extremely long simple, often roughened short small or lacking Terrestrial carnivory sharp incisors; long, conical canines; often carnassial cheek teeth; may have crushing molarsExample: dog -- simple short small Aquatic carnivory homodont, spiky, numerousExample: common dolphin -- simple or multichambered (cetaceans only) variable small or absent Sanguinivory very sharp upper incisors; reduced cheek teethExample: vampire bat grooved tubular, highly extensible long small or lacking Herbivory (except nectivores) incisors robust or absent; canines reduced or absent; diastema; cheek teeth enlarged with complex occlusal surfacesExample: beaver -- simple (hindgut fermenters) or multichambered (ruminants) long large Filter feeding none…

3. Shown below is the dental formula and digestive tract anatomy of three mammalian species (A, B, and C). What kind of diet would you expect each species to have? Support your answers with what you can infer from the dental formula and what you can see in the diagram. Broadly speaking, what accounts for the differences? Species A 3/3, 1/1, 4/4, 3/3 པར『ན་ cm 30 Species B 4/3, 1/1, 2/2, 4/4 cm 10 Species C 0/4, 0/0,3/3, 3/3 020