HOLES HUMAN ANATOMY AND PHYSIOLOGY
HOLES HUMAN ANATOMY AND PHYSIOLOGY
15th Edition
ISBN: 9781307233995
Author: SHIER
Publisher: MCG
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Chapter 13, Problem 2P
Summary Introduction

To distinguish:

Between the exocrine glands and endocrine glands.

Introduction:

There are two types of glandular systems:the endocrine glands and exocrine glands. These gland systems help the body in the regulation of the activity of cells and organs. They perform many functions to regulate body growth and metabolism.

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Digoxin: Intravenous Bolus - Two Compartment Model Drug Digoxin Route: IV Bolus Dose: 0.750 mg Plasma Concentration Time Profile Beta Alpha Time (hrs) Conc (ng/ml) LN (ng/ml) LN (ng/ml) LN 0.00 #NUM! #NUM! #NUM! 0.10 12.290 2.509 #NUM! #NUMI 0.60 6.975 1.942 #NUM! #NUMI 1.00 4.649 1.537 #NUM! #NUMI 2.00 2.201 0.789 #NUM! #NUM! 3.00 1.536 0.429 #NUM! #NUM! 4.00 1.342 0.294 #NUM! #NUM! 5.00 1.273 0.241 #NUM! #NUMI 6.00 1.238 0.213 #NUM! #NUM! 7.00 1.212 0.192 #NUM! #NUM! 8.00 1.188 0.172 #NUMI #NUM! 9.00 1.165 0.153 #NUM! #NUMI 10.00 1.143 0.134 #NUMI #NUM! 11.00 1.122 0.115 #NUM! 12.00 1.101 0.096 #NUMI 13.00 1.080 0.077 #NUMI 16.00 1.020 0.020 #NUMI 24.00 0.876 -0.132 #NUMI Pharmacokinetic Parameters Parameter Value Alpha B Beta Units ng/ml hr-1 ng/ml hr-1 CO ng/ml H.C AUC ng x hr/ml Vc Vbeta Vss C L/hr TK (alpha) hr TX (beta) days 5+ F3 F4 F5 0+ F6 F7 % 6 95 14 #3 29 & t F8 F9 FW EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg rabbits following a bolus IV injection of 10mg/kg. Time (minutes) Serum Linuron Levels (ug/ml) following IV dose 10 15.48 20 8.60 30 5.90 45 3.78 60 2.42 90 1.49 120 0.93 180 0.60 240 0.41 300 0.29 360 0.22 Analyze this data and perform the necessary calculations to determine the following pharmacokinetic parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points possible). You do NOT need to submit graphs or data tables. Give the terminal regression line equation and R or R² value: Give the x axis (name and units, if any) of the terminal line: Give the y axis (name and units, if any) of the terminal line: Give the residual regression line equation and R or R² value: Give the x axis (name and units, if any) of the residual line: Give the y axis (name and units, if any) of the residual line:

Chapter 13 Solutions

HOLES HUMAN ANATOMY AND PHYSIOLOGY

Ch. 13 - Prob. 11PCh. 13 - Prob. 12PCh. 13 - Prob. 13PCh. 13 - Prob. 14PCh. 13 - Prob. 15PCh. 13 - Prob. 16PCh. 13 - Prob. 17PCh. 13 - Prob. 18PCh. 13 - Prob. 19PCh. 13 - Prob. 20PCh. 13 - Prob. 21PCh. 13 - Prob. 22PCh. 13 - What effects does oxytocin produce in females?Ch. 13 - Prob. 24PCh. 13 - Prob. 25PCh. 13 - Prob. 26PCh. 13 - Prob. 27PCh. 13 - Prob. 28PCh. 13 - Prob. 29PCh. 13 - 30 How does the negative feedback system of the...Ch. 13 - Prob. 31PCh. 13 - Prob. 32PCh. 13 - Prob. 33PCh. 13 - Prob. 34PCh. 13 - Prob. 35PCh. 13 - Prob. 36PCh. 13 - Prob. 37PCh. 13 - How are blood concentrations of aldosterone and...Ch. 13 - Prob. 39PCh. 13 - Prob. 40PCh. 13 - Prob. 41PCh. 13 - Prob. 42PCh. 13 - Prob. 43PCh. 13 - Prob. 44PCh. 13 - Prob. 45PCh. 13 - Prob. 46PCh. 13 - Prob. 47PCh. 13 - Distinguish between physical stress and...Ch. 13 - Prob. 49PCh. 13 - Prob. 50PCh. 13 - Prob. 51PCh. 13 - Prob. 1CACh. 13 - Prob. 2CACh. 13 - Prob. 3CACh. 13 - Explain how hormones can be grouped on the basis...Ch. 13 - Prob. 5CACh. 13 - List the steps of the action of most nonsteroid...Ch. 13 - Prob. 7CACh. 13 - Prob. 8CACh. 13 - Prob. 9CACh. 13 - Prob. 10CACh. 13 - Prob. 11CACh. 13 - Prob. 12CACh. 13 - Prob. 13CACh. 13 - Prob. 14CACh. 13 - Prob. 15CACh. 13 - Prob. 16CACh. 13 - Prob. 17CACh. 13 - Prob. 18CACh. 13 - Prob. 19CACh. 13 - Prob. 20CACh. 13 - Prob. 21CACh. 13 - Prob. 22CACh. 13 - Prob. 23CACh. 13 - Prob. 24CACh. 13 - Prob. 25CACh. 13 - Prob. 26CACh. 13 - Prob. 27CACh. 13 - Prob. 28CACh. 13 - Prob. 29CACh. 13 - Prob. 30CACh. 13 - Prob. 31CACh. 13 - Prob. 32CACh. 13 - Prob. 33CACh. 13 - Prob. 34CACh. 13 - Prob. 35CACh. 13 - Prob. 36CACh. 13 - Prob. 37CACh. 13 - Describe hormonal and nervous responses to stress....Ch. 13 - Prob. 39CACh. 13 - Prob. 1IACh. 13 - Prob. 2IACh. 13 - Prob. 3IACh. 13 - Growth hormone is administered to people who have...Ch. 13 - Prob. 5IACh. 13 - Prob. 6IACh. 13 - Prob. 7IA
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