
Concept explainers
To analyze:
The time taken by the DNA polymerase to complete the replication process of the entire DNA molecule of the shortest chromosome, by moving uninterruptedly from one end to the other end. Also figure out whether
Given:
The DNA polymerase proceeds uninterruptedly on the DNA strand, from one end to the other end to synthesize the new DNA strand. Addition of
Introduction:
The division of cells in a cell cycle involves two phases: interphase and mitotic phase. Replication of the genetic material takes place during synthesis phase or S phase of the interphase. DNA polymerase is responsible for DNA replication in both eukaryotes and prokaryotes.

Explanation of Solution
The rate at which DNA polymerase proceeds the formation of new DNA strand is 50 bp/s. Therefore, to replicate a DNA strand of
The synthesis phase of a mammalian cell is 8 hours long, and the entire replication process occurs during this time. This indicates that there must be multiple DNA polymerase complexes involved in this process. Hence more than one replication origin sites must be there, where the enzyme would attach itself to synthesize a new strand.
Therefore, it can be concluded that there are many replication origin sites where DNA polymerase enzyme work simultaneously, to complete the synthesis of new DNA strand.
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Chapter 13 Solutions
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