EBK MICROBIOLOGY
12th Edition
ISBN: 8220100659720
Author: CASE
Publisher: PEARSON
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Chapter 13, Problem 1MCQ
Summary Introduction
Introduction:
Virus that infect and replicate inside the bacteria is called bacteriophage or phage. Bacteriophages replicate their genetic material by lytic and lysogenic cycles. During the replication process, it injects the viral genetic material (DNA or RNA) to the host target cell with the help of some essential proteins and helps to replicate the number of copies.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
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The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 13 Solutions
EBK MICROBIOLOGY
Ch. 13 - Why do we classify viruses as obligatory...Ch. 13 - List the four properties that define a virus, what...Ch. 13 - Describe the four morphological classes of...Ch. 13 - DRAW IT Label the principal events of attachment,...Ch. 13 - Compare biosynthesis of a + stranded RNA and a ...Ch. 13 - Prob. 6RCh. 13 - Why is it difficult to determine the etiology of a...Ch. 13 - Prob. 8RCh. 13 - Plant viruses can be cultured in (c) __________.Ch. 13 - NAME IT Identify the viral family that infects...
Ch. 13 - Prob. 1MCQCh. 13 - The molecule serving as mRNA can be incorporated...Ch. 13 - Prob. 3MCQCh. 13 - Prob. 4MCQCh. 13 - An example of lysogeny in animals could be a. slow...Ch. 13 - The ability of a virus to infect an organism is...Ch. 13 - Which of the following statements is false? a....Ch. 13 - Prob. 8MCQCh. 13 - Prob. 9MCQCh. 13 - Prob. 10MCQCh. 13 - Discuss the arguments for and against the...Ch. 13 - In some viruses, capsomeres function as enzymes as...Ch. 13 - Why was the discovery of simian AIDS and feline...Ch. 13 - Prophages and proviruses have been described as...Ch. 13 - Prob. 1CAECh. 13 - A newborn female developed extensive vesicular and...Ch. 13 - Prob. 3CAE
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