The physical examination tests that can assess the function of each of the cranial nerves. Introduction: The stimuli from the brain and to the brain are transferred by a group of nerves called cranial nerves. These are the components of the peripheral nervous system (PNS) and are always present in pairs. There exist a total of 12cranial nerves. Based on the motor and sensory impulses, these are classified as sensory, motor, and mixed cranial nerve.

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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Chapter 13, Problem 1CYU

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The physical examination tests that can assess the function of each of the cranial nerves.

Introduction:

The stimuli from the brain and to the brain are transferred by a group of nerves called cranial nerves. These are the components of the peripheral nervous system (PNS) and are always present in pairs. There exist a total of 12cranial nerves. Based on the motor and sensory impulses, these are classified as sensory, motor, and mixed cranial nerve.

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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