Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780321962751
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 1.3, Problem 1CC
Contrast inductive reasoning with deductive reasoning
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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
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Mutation 1
Mutation 2
There is currently a H5N1 cattle outbreak in North America.
According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."
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Mechanisms 2:
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You have a bacterial strain with the CMU operon:
a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a
kinase and regulator corresponding to a two-component system. The cmu operon is
activated when Pep 1 is added to the growth media.
Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon.
Pep1 cmu-kinase cmu-regulator
You also have these genetic components in other strains:
b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a
series of multiple operons that together encode a transformasome (cellular machinery
for transformation).
c) the gene cl (a repressor).
d) the promoter X, which includes a cl binding site (and in the absence of cl is active).
e) the gene gp (encoding a green fluorescence protein).
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Chapter 1 Solutions
Campbell Biology in Focus (2nd Edition)
Ch. 1.1 - Starting with the molecular level in Figure 1.3,...Ch. 1.1 - Identify me theme or themes exemplified by (a) the...Ch. 1.1 - WHAT IF? For each theme discussed in this section...Ch. 1.2 - How is a mailing address analogous to biologys...Ch. 1.2 - Explain why editing is an appropriate metaphor for...Ch. 1.2 - DRAW IT Recent evidence indicates that fungi and...Ch. 1.3 - Contrast inductive reasoning with deductive...Ch. 1.3 - What qualitative observation led to the...Ch. 1.3 - Why is natural selection called a theory?Ch. 1.3 - How does science differ from technology?
Ch. 1 - All the organisms on your campus make up A. an...Ch. 1 - Which of the following best demonstrates the unity...Ch. 1 - Prob. 3TYUCh. 1 - Prob. 4TYUCh. 1 - Prob. 5TYUCh. 1 - DRAW IT With rough sketches, draw a biological...Ch. 1 - SCIENTIFIC INQUIRY Based on the results of the...Ch. 1 - Prob. 9TYUCh. 1 - FOCUS ON EVOLUTION In a short essay (100-150),...Ch. 1 - FOCUS ON INFORMATION A typical prokaryotic cell...Ch. 1 - SYNTHESI7F YOUR KNOWLEDGE Can you pick out the...
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- You have identified a new species of a Gram-positive bacteria. You would like to screen their genome for all proteins that are covalently linked to the cell wall. You have annotated the genome, so that you identified all the promoters, operons, and genes sequences within the operons. Using these features, what would you screen for to identify a set of candidates for proteins covalently linked to the bacterial cell wall.arrow_forwardBelow is a diagram from a genomic locus of a bacterial genome. Each arrow represents a coding region, and the arrowheads indicate its orientation in the genome. The numbers are randomly assigned. Draw the following features on the diagram, and explain your rationale for each feature: 10 12 合會會會會長 6 a) Expected transcriptions, based on known properties of bacterial genes and operons. How many proteins are encoded in each of the transcripts? b) Location of promoters (include rationale) c) Location of transcriptional terminators (include rationale) d) Locations of Shine-Dalgarno sequences (include rationale)arrow_forwardSample excuse letter in school class for the reasons of headaches and dysmenorrhea caused by menstrual cyclearrow_forward
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