Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 12.3, Problem 2CC
How does MPF allow a cell to pass the G2 phase Checkpoint and enter mitosis? (See Figure 12.16.)
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Chapter 12 Solutions
Campbell Biology (11th Edition)
Ch. 12.1 - How many chromosomes are drawn in each part of...Ch. 12.1 - WHAT IF? A chicken has 78 chromosomes in its...Ch. 12.2 - How many chromosomes are shown in the illustration...Ch. 12.2 - Compare cytokinesis in animal cells and plant...Ch. 12.2 - During which stages of the cell cycle does a...Ch. 12.2 - Compare the roles of tubulin and actin during...Ch. 12.2 - A kinetochore has been compared to a coupling...Ch. 12.2 - MAKE CONNECTIONS What other functions do actin...Ch. 12.3 - In Figure 12.14, why do the nuclei resulting from...Ch. 12.3 - How does MPF allow a cell to pass the G2 phase...
Ch. 12.3 - MAKE CONNECTIONS Explain how receptor tyrosine...Ch. 12 - Differentiate between these terms: chromosome,...Ch. 12 - In which of the three phases of interphase and the...Ch. 12 - Explain the significance of the G1, G2, and M...Ch. 12 - Through a microscope, you can see a cell plate...Ch. 12 - Vinblastine is a standard chemotherapeutic drug...Ch. 12 - One difference between cancer cells and normal...Ch. 12 - The decline of MPF activity at the end of mitosis...Ch. 12 - In the cells of some organisms, mitosis occurs...Ch. 12 - Which of the following does not occur during...Ch. 12 - Cell A has half as much DNA as cells B, C, and D...Ch. 12 - The drug cytochalasin B blocks the function of...Ch. 12 - VISUAL SKILLS The light micrograph shows dividing...Ch. 12 - DRAW IT Draw one eukaryotic chromosome as it would...Ch. 12 - EVOLUTION CONNECTION The result of mitosis is that...Ch. 12 - SCIENTIFIC INQUIRY Although both ends of a...Ch. 12 - WRITE ABOUT A THEME: INFORMATION The continuity of...Ch. 12 - SYNTHESIZE YOUR KNOWLEDGE For selected answers,...
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- During which phase of mitosis do the centrosomes begin to migrate to opposite sides of the cell?arrow_forward5.) Using Figure 4.4, identify the phase of mitosis that each of the following events occur in. migration of sister chromatids to the poles condensation of chromatin into chromosomes formation of a nuclear membranearrow_forwardA hypothetical poison prevents transcription factors from binding to the gene for tubulin proteins. What impact would this have on mitosis, and why?arrow_forward
- In the following study, the investigators wanted to determine the role of cyclin B in controlling the cell cycle. Earlier researchers had found that extracts made from frog eggs (Xenopus) contained all the necessary proteins and machinery required for DNA replication. This included proteins that regulated the mitosis promoting factor (MPF). At the time of this study, cyclin B was show to affect MPF activity and the research group wanted to test using Xenopus egg extract in an assay. In Figure 1 (a) MPF activity was tested for its ability to phosphorylate Histone (H1) in sperm chromatin over a certain period of time. Additionally, the cyclin B concentration in the extract was measured. In figure 1b, the extract was tested after treatment with RNase which degraded only the mRNA and not RNA or FRNA in the extract. Knowing that cyclin B is a short-lived protein, why do you suppose the graph shows the results you see in figure 1b?arrow_forwardDuring which phase of mitosis will the sister chromatids pull apart from one another to move to opposite sides of the cell?arrow_forward. 2 3 1 4 . 5 6 I 7. .. (a) Identify the point in mitosis at which separase cleaves the protein complex that holds sister chromatid pairs together. In normal cells, separase is kept in an inactive state until it is needed. Explain how the progression of cells past sequential cell cycle checkpoints and the activity of enzymes such as separase is controlled by interactions between two major groups of regulatory proteins. (b) Identify an independent variable in the experiment graphed in Figure 1. Based on the data in Figure 1, identify a control that shows that Sepin-1 rather than something else in the culture medium is inhibiting the growth of the cancer cells. (c) Based on the data in Table 1, describe the general relationship between the sensitivity of cells to Sepin-1 and the concentration of separase in the cells. Use the Figure 1 data to calculate the ratio between the amount of Sepin-1 required to kill 50% of the cells in the cell line that is most sensitive to the compound and the…arrow_forward
- The anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death?arrow_forwardWhich of the following diagrams correctly depicts the orientation of microtubules during metaphase of mitosis? A B C OA I (-) (+) (+) (+) (+) (+) (+) (+) (+)50 (+) == (-) XX [(+) (-) E (-) J ++) (+) - (+) (-) (+) 11 15+ E (+) (-) 50 at &&05 (-) 50) (+) (-) (-) (+) (-) D E (+) (+) (+) D (-) St (+) coff (+) (-) (+) (+) (-) (-) (+) (-) (-) affere XXX (-)- (-) ++) (+) (-) (-) (-) (-) Karrow_forwardWithin which phase of mitosis does chromatin condense into small manageable chromosomal units?arrow_forward
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