BIOL 1010/1020 CLASS ONLY CONNECT
BIOL 1010/1020 CLASS ONLY CONNECT
14th Edition
ISBN: 9781260038644
Author: Mader
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 12, Problem 4TC

There are not enough living heats available to meet the need for heart transplants. What are some of the major problems a manufacturer would have to overcome when attempting to design an artificial heart that last for years inside a patient's body?

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Blood is pushed out of the heart through a large vessel, called the aorta. The aorta then divides into smaller and smaller blood vessels, eventually reaching vessels called capillaries. Capillaries are so small that oxygen and nutrients can diffuse across the vessel walls and into the tissues of the body, with CO2 and waste diffusing back into the blood.   Let's say that the cross-sectional area of the aorta is 1 cm2 = 100 mm2. The blood pumps through the aorta at 100 mm/s but only through the capillaries at 1 mm/s. If each capillary has a cross-sectional area of 20 mm2, how many capillaries must there be in the body?   Note: these numbers are not physiologically correct, but were chosen to make the math easier. The blood velocity through the aorta is closer to 300 mm/s. The capillaries have a total cross-sectional area of ~600,000 mm2 (6000 cm2), with a blood flow rate closer to 0.2 mm/s.
One of the current major areas of research in heart transplants is the use of pig hearts for human transplants. Since pig and human hearts are virtually identical anatomically, researchers feel that it can make hearts available to everyone that needs one. Should the organs of pigs (or any other animals) be used to preserve the lives of humans? Why or why not?
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BIOL 1010/1020 CLASS ONLY CONNECT

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