EBK BIOLOGY
EBK BIOLOGY
6th Edition
ISBN: 8220106777640
Author: Maier
Publisher: PEARSON
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Chapter 12, Problem 4LTB
Summary Introduction

Antibiotics are the drugs that kill microbes including bacteria. Antibiotics are effective in controlling infections through their immune system.

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Different strains of Streptococcus pyogenes have different virulence factors, giving these microbes much versatility. Virulence factors include which of the following? Choose one or more: A.A capsule that, when thick, will help the organism avoid phagocytosis by macrophages B.A cell wall containing lipoteichoic acid, thought to facilitate adherence to pharyngeal epithelial cells C.Enzymes that lyse blood cells (streptolysins) D.The production of several endotoxins called streptococcal pyogenic endotoxins (SPEs)
You are designing a phage therapy for a cystic fibrosis patient with an multi-antibiotic resistant Mycobacterium infection. The Mycobacterium infection is preventing the patient from taking immunosuppressant drugs that are needed for a successful lung transplant. The idea is that introducing the right phage to the patient will kill the Mycobacterium cells and allow the patient to go on immunosuppressant drugs that will ensure the new lung is not rejected by the body.  You need to find a phage that infects the Mycobacterium you isolated from the patient. Which TWO options have the highest chance of success? A. Screening a colleague's library of known Mycobacterium phages for phage that infect the patient's Mycobacterium isolate   b. Choosing likely candidates from analysis of phage 16S rRNA phylogeny in the tree of life   C. Isolating new phage from soil using a plaque assay with the Mycobacterium isolate   D. Obtaining a very well-studied phage, such as T4 bacteriophage, that…
You are designing a phage therapy for a cystic fibrosis patient with an multi-antibiotic resistant Mycobacterium infection. The Mycobacterium infection is preventing the patient from taking immunosuppressant drugs that are needed for a successful lung transplant. The idea is that introducing the right phage to the patient will kill the Mycobacterium cells and allow the patient to go on immunosuppressant drugs that will ensure the new lung is not rejected by the body.  You finally find a phage that you think will work because it attaches to and injects its genome into the patient's Mycobacterium isolate. Next, you need to be sure of what characteristics of the phage infection cycle? Pick all that are true  A. That the phage delivers new antibiotic resistance genes to Mycobacterium via transduction B. That the correct proteins are expressed during the phages metabolism C. That the infection is lytic D.That lysogeny is the primary infection pathway
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