EBK INTRODUCTION TO THE PRACTICE OF STA
EBK INTRODUCTION TO THE PRACTICE OF STA
8th Edition
ISBN: 9781319116828
Author: Moore
Publisher: VST
Question
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Chapter 12, Problem 49E

(a)

To determine

To find: The expression of contrast for each of the treatments in terms of their respective means.

(a)

Expert Solution
Check Mark

Answer to Problem 49E

Solution: The expression of contrast for the experiment including the treatment of Placebo verses average of two low dose treatment is given below:

ψ1=μ10.5μ20.5μ4

The expression of contrast for the experiment including the treatment of difference between high A and low A verses high B and low B is given below:

ψ2=(μ3μ2)(μ5μ4)

Explanation of Solution

Calculation: The average of means of low A and low B treatment is 0.5(μ2+μ4) and the mean of Placebo treatment is μ1. Therefore, null and alternative hypotheses can be formed as follows:

H0:ψ1=0Ha:ψ1>0

Null hypotheses represent that there is no difference in the Placebo treatment and average of low A and low B treatment, which is represented as below:

H0:μ1=0.5(μ2+μ4)

Hence, on equating ψ1=0, the expression of contrast can be obtained as given below:

μ10.5(μ2+μ4)=0, since ψ1 is equal to 0.

The difference of means of low A and high A treatment is (μ3μ2) and the difference of means of high B and low B treatment is (μ5μ4). Therefore, null and alternative hypotheses can be formed as follows:

H0:ψ2=0Ha:ψ2>0

Null hypotheses represent that there is no difference in the difference of low A and high A treatment and difference of high B and low B treatment, which is represented as below:

H0:(μ3μ2)=(μ5μ4)

Hence, on equating ψ1=0, expression of contrast can be obtained as given below:

(μ3μ2)(μ5μ4)=0, since ψ2=0

The coefficients of contrast for the contrast ψ1 are given below:

a1=1a2=0.5a3=0a4=0.5

a5=0

The coefficients of contrast for the contrast ψ2 are given below:

a1=0a2=1a3=1a4=1

a5=1

(b)

To determine

To find: The sample and standard error for each of the contrast.

(b)

Expert Solution
Check Mark

Answer to Problem 49E

Solution: The sample of contrast c1 for the contrast expression ψ1 is 3.9_ and the sample of contrast c2 for the contrast expression ψ2 is 2.35.

The standard error for the contrast c1 is 2.1353 and the standard error for the contrast c2 is 3.487.

Explanation of Solution

Calculation: The value of contrast c1 can be calculated by using the formula given below:

c1=iaix¯i=(1×11.80)+((0.5)×15.25)+((0.5)×16.15)=3.9

The value of contrast c2 can be calculated by using the formula given below:

c2=iaix¯i

c2=((1)×15.25)+(1×18.55)+(1×16.15)+((1)×17.10)=2.35

Standard error can be calculated by using the formula given below:

SEc1=spooledai2ni

Pooled standard deviation can be calculated as given below:

sp=(n11)s12+(n21)s22++(n51)s22n1+n2+n3+n4+n5k=(51)17.20+(51)13.10++(51)12.50(5+5+5+5+5)5=3.487

For the first contrast, the standard error SEc1 can be calculated as given below:

SEc1=3.48714+(0.5)24+(0.5)24=3.487×0.375=2.1353

For the second contrast, the standard error SEc2 can be calculated as given below:

SEc1=3.48714+14+14+14=3.487×1=3.487

Interpretation: Therefore, it can be concluded that for the first contrast, the estimated value of standard deviation is 2.1353 and for the second contrast, the estimated value of standard deviation is 3.487.

(c)

To determine

To test: The significance test for each of the contrast and summarize the obtained results.

(c)

Expert Solution
Check Mark

Answer to Problem 49E

Solution: The test statistic for contrast of the experiment including the treatment of Placebo verses average of two low dose treatment is 0.0414 and the test statistics for contrast for the experiment including the treatment of difference between high A and low A verses high B and low B is 0.2540. For the first contrast, the result is significant but for the second contrast the result is insignificant.

Explanation of Solution

Calculation: Test statistic can be calculated by using following formula, which is mentioned below:

t=cSEc

To calculate the test statistic for first contrast, the value of c1=3.9 and is substituted in the formula mentioned above:

t=cSEc=3.92.1353=1.8264

The total sample size of rats is 25. There are five groups, which are represented by k.

The degree of freedom for contrast can be obtained as shown below:

Nk=255=20

The P-value can also be calculated by the software Microsoft Excel by using the following command:

EBK INTRODUCTION TO THE PRACTICE OF STA, Chapter 12, Problem 49E , additional homework tip  1

Insert the values of x and degree of freedom, which are –1.8264 and 20, respectively. After this, press enter and the output is shown below in the snapshot:

EBK INTRODUCTION TO THE PRACTICE OF STA, Chapter 12, Problem 49E , additional homework tip  2

Hence, the P- value is obtained as 0.0414, which is less than the significance level 0.05, so the decision is to reject the null hypothesis.

To calculate the test statistic for second contrast, the value of c2=2.35 and SEc2=3.487 is substituted in the formula mentioned above:

t=cSEc=2.353.487=0.6739

The P-value can also be calculated by the software Microsoft Excel by using the following command:

EBK INTRODUCTION TO THE PRACTICE OF STA, Chapter 12, Problem 49E , additional homework tip  3

Insert the values of x and degree of freedom, which is 0.6739 and 20, respectively. After this, press enter and the output is shown below in the snapshot:

EBK INTRODUCTION TO THE PRACTICE OF STA, Chapter 12, Problem 49E , additional homework tip  4

Hence, the P- value is obtained as 0.2540, which is greater than the significance level 0.05, so the decision is to accept the null hypothesis.

Conclusion: Therefore, it can be concluded that the result is significant for the first contrast and the result is not significant for the second contrast.

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