Modified Mastering Biology With Pearson Etext -- Standalone Access Card -- For Biological Science (7th Edition)
7th Edition
ISBN: 9780135276556
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 12, Problem 3TYK
Progression through the cell cycle is regulated by oscillations in the concentration of which type of molecule?
a. p53, Rb, and other tumor suppressors
b. receptor tyrosine kinases
c. cyclins
d. cyclin-dependent kinases
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Students have asked these similar questions
P53 is a tumor suppressor protein. The protein is present in the cell at all times but is activated by protein kinases that are, in turned activated by DNA damage. What would be the result of a mutation of the P 53 gene in cell that resulted in a form of P53 that was permanently active?
Group of answer choices
A. the cell cycle would be inhibited in all cells in a tumor if it forms
B. the cell cycle would be inhibited
C. the cell would form a tumor
D. the cell has a higher probability of forming a tumor
E. the cell cycle of all cells in the body would be inhibited
What is a primary function of tumor suppressor genes?a. stop all cells from dividingb. stop certain cells from dividingc. help oncogenes produce oncoproteinsd. allow the cell to skip certain phases of the cellcycle
Describe the relationship between cell cycle and link to cancer. Use the following terms in your explanation: tumor, oncogene, tumor suppressor, apoptosis.
Chapter 12 Solutions
Modified Mastering Biology With Pearson Etext -- Standalone Access Card -- For Biological Science (7th Edition)
Ch. 12 - 1. Which statement about the daughter cells...Ch. 12 - After S phase, what comprises a single chromosome?...Ch. 12 - Progression through the cell cycle is regulated by...Ch. 12 - 4. What major events occur during anaphase of...Ch. 12 - 5. Identify at least two events in the cell cycle...Ch. 12 - 6. What evidence suggests that during anaphase,...Ch. 12 - 7. Evaluate each of the following defects. Which...Ch. 12 - Prob. 8TYUCh. 12 - Prob. 9TYPSSCh. 12 - Prob. 10TYPSS
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- Chemotherapy utilizes chemicals to interrupt various parts of the cell cycle, targeting rapidly growing cells. Taxol® is an example of a drug that prevents mitosis phase from occurring. How this Taxol useful as a cancer treatment and how might targeting rapidly growing cells explain common chemotherapy side effects such as hair loss and nausea? A. Taxol will stop the tumor from growing, but unfortunately it also impacts other fast-growing cells (like hair follicles and stomach lining cells), so normal cells get damaged as well. B. Taxol will stop the tumor from continuing to divide, but unfortunately it also impacts other readily dividing cells (like hair follicles and stomach lining cells), so normal cells get damaged as well. C. Taxol will stop the tumor from copying DNA, but unfortunately it also impacts DNA replication in other cells (like hair follicles and stomach lining cells), so normal cells don't get to continue through…arrow_forwardWhat would be the most likely effect of a mutation that causes cyclin B to be unable to bind to CDK? a. Cells pass through the G2/M checkpoint and enter mitosis even when DNA has not been replicated. b. Cells never pass through the G1/S checkpoint. c. Cells pass through mitosis more quickly than nonmutated cells. d. Cells fail to pass through the G2/M checkpoint and do not enter mitosis.arrow_forwardA tumor suppressor gene regulates the cell cycle; an example is . Select one: a. positively, p21 b. negatively, cyclin c. positively, retinoblastoma d. negatively, retinoblastoma e. positively, RAS Cycle HW due Jump to. 4) Next pa cancer stem cellsarrow_forward
- Which negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur? a. p53 b. p21 c. retinoblastoma protein (Rb) d. cyclin-dependent kinase (Cdk)arrow_forwardSome types of cancers are treated with surgery, chemotherapy, stem cell replacement or radiation, similar to ultraviolet light. Why might it be beneficial to irradiate cancer cells? Choose the Best answer. A. it kills off all the cancer cells. B. it forces all cancer cells into G0 C. it will halt cell division and possibly be forced into apoptosis D. it could kill off the cancer cells, halt cell division or possibly force the cell into apoptosisarrow_forwardWhich of the following is NOT an example of fail-safe mechanisms that prevent the irregular cell divisions characteristic of cancer? a.Shortening of telomeres b.Cell division limit c.Mutation in a tumor suppressor gene d.Triggered cell deatharrow_forward
- What would be the effect on the following processes in a cancer cells treated with Drug X. Match the process with the likely effect of the drug. Protein Translation Apoptosis Cell Proliferation Production of new blood vessels A. Inhibited B. Activatedarrow_forwardWhy would the failure of the p53 tumor supressor gene be more likely to cause cancer in a seventy year old person compared to a ten year old person? Group of answer choices A. the p53 gene never works well in old people B. cells divide more rapidly as people get older C.The seventy year old is more likely to have pre-existing failures in cell cycle control D. there are fewer mutations in genes controlling the cell cycle in older peoplearrow_forwardHow does the dysregulation of cell cycle checkpoints contribute to the development of cancer?arrow_forward
- A tumor suppressor gene ___regulates the cell cycle; an example is _____. Select one: a. negatively, cyclin b. positively, retinoblastoma c. positively, p21 d. negatively, retinoblastoma e. positively, RASarrow_forwardMuch remains unknown about the rapid, uncontrolled growth, or what causes a tumor to metastasize. Scientists do know that cancer cells come from normal healthy cells that have had some type of damage done to the genes that aid in the production of the regulatory proteins for the cell cycle. What causes this damage? a proto-oncogenes b mutations c enzymes d tumor suppressorsarrow_forwardDescribe how tumor suppressors function to stop the cell cycle until certain events are completedarrow_forward
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