Organic Chemistry (6th Edition)
6th Edition
ISBN: 9781260119107
Author: Janice Gorzynski Smith
Publisher: McGraw Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 12, Problem 39P
Interpretation Introduction
Interpretation: The product formed when reaction only occurs on
Concept introduction: The coenzyme nicotinamide adenine dinucleotide,
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
4. Glycolysis is a metabolic pathway that converts glucose into pyruvate while synthesizing
high-energy molecules. During one step of Glycolysis, glucose-6-phosphate (an aldose) is
converted to fructose-6-phosphate (a ketose) via an ene-diol intermediate.
OH OH O
OP OH OH
ОН
ОН
glucose-6-phosphate
OH OH OH
OP OH
fructose-6-phosphate
Draw arrow pushing mechanism to describe this isomerization. Use B: and HA as surrogates
for basic/acidic amino acid residues.
An important step in the glycolysis pathway for catabolizing glucose is the hydride
transfer from an hemithioacetal to the acceptor NAD*. Indicate with curved arrows the flow of
electrons in this step.
Enzyme
Enzyme
BH*
B:
H
H-O-H
H-
OH
`NH2
H-
-OH
NH2
CH,OPO,2
CH,OPO,
Hemithioacetal
Thioester
Drinking methanol can cause blindness in humans, as well as a severe acidosis that may be life threatening. Methanol is toxic because it is converted in the liver to formaldehyde and formic acid by the enzymes alcohol dehydrogenase and aldehyde dehydrogenase. Methanol poisoning is treated with dialysis and infusions of bicarbonate and ethanol. Explain why each treatment is used.
Chapter 12 Solutions
Organic Chemistry (6th Edition)
Ch. 12.1 - Prob. 1PCh. 12.3 - Problem 12.2 What alkane is formed when each...Ch. 12.3 - Prob. 3PCh. 12.3 - Prob. 4PCh. 12.3 - Prob. 5PCh. 12.3 - Prob. 6PCh. 12.3 - Compound Molecular formula before...Ch. 12.4 - Problem 12.8 Draw the products formed when...Ch. 12.5 - Prob. 9PCh. 12.5 - Prob. 10P
Ch. 12.5 - Problem 12.11 (a) Draw the structure of a compound...Ch. 12.5 - Prob. 12PCh. 12.5 - Prob. 13PCh. 12.6 - Problem 12.14 Draw the products of each...Ch. 12.8 - Prob. 15PCh. 12.8 - Problem 12.16 Draw all stereoisomers formed when...Ch. 12.9 - Prob. 17PCh. 12.9 - Problem 12.18 Draw the products formed when both...Ch. 12.10 - Problem 12.19 Draw the products formed when each...Ch. 12.10 - Prob. 20PCh. 12.10 - Prob. 21PCh. 12.11 - Problem 12.22 Draw the products formed when each...Ch. 12.11 - Prob. 23PCh. 12.12 - Problem 12.24 Draw the organic products in each of...Ch. 12.13 - Prob. 25PCh. 12 - 12.29 Draw the products formed when A is treated...Ch. 12 - Prob. 30PCh. 12 - Prob. 31PCh. 12 - Prob. 32PCh. 12 - Prob. 33PCh. 12 - Draw the organic products formed when cyclopentene...Ch. 12 - Draw the organic products formed when allylic...Ch. 12 - Prob. 39PCh. 12 - Prob. 40PCh. 12 - Prob. 41PCh. 12 - What alkene is needed to synthesize each 1,2-diol...Ch. 12 - 12.48 Draw the products formed in each oxidative...Ch. 12 - What alkene or alkyne yields each set of products...Ch. 12 - Prob. 47PCh. 12 - Prob. 48PCh. 12 - Prob. 49PCh. 12 - Prob. 50PCh. 12 - 12.57 Draw the product of each asymmetric...Ch. 12 - 12.60 Identify A in the following reaction...Ch. 12 - Prob. 58PCh. 12 - 12.62 It is sometimes necessary to isomerize a cis...Ch. 12 - 12.63 Devise a synthesis of each compound from...Ch. 12 - Prob. 61P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- How many glycosidic bonds does the following molecule have?arrow_forwardThe following is the structure of salicin, a bitter-tasting compound found in the bark of willow trees: The aromatic ring portion of this structure is quite insoluble in water. How would forming a glycosidic bond between the aromatic ring and β - D -glucose alter the solubility?arrow_forward14. Label the glycosidic bond. Is this a reducing sugar? 6 CH₂OH 1 CH₂OH 2 5 4 3 OH OH LO 5 OH OH 1 4 OH 3 OHarrow_forward
- Draw the structure of the intermediate (first product) of the following oxidation reaction. CH3CH,CH,CH,OHarrow_forwardidentify the structure of the major organic product formed in the following reaction. uestion 43 entify the structure of the major organic product formed in the following reaction. COOH O COOH -COOCH3 -COOH COOH CH₂OH COCI Heat ???arrow_forwardWrite the structure of the following compounds: γ-lactolarrow_forward
- 11. In phase 2 metabolic transformation chloramphenicol the primary alcohol is converted to a glucuronide conjugate. Draw chemical structure of the product. Provide the name of enzyme that catalyze this metabolic reaction. OH CHCI2 O,N- но 22arrow_forward5)A certain aerobic organism is able to metabolize the followingglycolipid CH,OH H H OH H HO OH A.Draw the 2 resulting structures that would occur upon initial hydrolysis of the O-glycosidic bond.arrow_forwardCholesterol-lowering drugs commonly target O HMG-COA synthase, the enzyme that catalyzes the synthesis of mevalonate O pyruvate decarboxylase complex, which catalyzes the synthesis of acetyl-CoA O mevalonate, an isoprene O HMG-COAreductase, the rate-limiting enzyme in cholesterol biosynthesis O HMG-CoA synthase, the enzyme that catalyzes the first step in cholesterol biosynthesisarrow_forward
- a. In an aqueous solution, d-glucose exists in equilibrium with two six-membered ring compounds. Draw the structures of these compounds.b. Which of the six-membered ring compounds will be the major product?arrow_forwardOne pathway for the metabolism of D-glucose 6-phosphate is its enzyme-catalyzed conversion to D-fructose 6-phosphate. Show that this transformation can be accom- plished as two enzyme-catalyzed keto-enol tautomerisms. СНО CH,OH C=0 enzyme catalysis Но Но H OH H H. O- H- -HO- ČH,OPO, ČH,OPO, D-Glucose 6-phosphate D-Fructose 6-phosphatearrow_forwardIdentify the products of the two reactions of glucose. COOH HOH Н НО H Н HOH Н- -OH CH₂OH Н НО CH2OH -OH H- H -Н -OH OH CH₂OH Cu2+/OH- CHO O НО н H OH H-+ -OH CH₂OH Н но- Н- Н- CHO HOH но- Н- -Н -ОН H-OH CHO CHO -ОН -Н -ОН -ОН CH2OH Answer Bank 0 CH3 H— НО -OH -H H-OH H-OH CH₂OH H₂/Pt CHO H-OH HO-H H -ОН H OH COOH CH₂OH =0 HO-H H- Н -ОН -OH CH₂OHarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningIntroductory Chemistry: A FoundationChemistryISBN:9781337399425Author:Steven S. Zumdahl, Donald J. DeCostePublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning
- Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Introductory Chemistry: A Foundation
Chemistry
ISBN:9781337399425
Author:Steven S. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Organic Chemistry
Chemistry
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:Cengage Learning
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning